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[托斯卡纳地区的恶性高热:1986年至1990年五年期间的一项研究]

[Malignant hyperthermia in Tuscany: a study of a five year period from 1986 to 1990].

作者信息

Logi G, Tanteri M, Lucchesi A M, Pellegrini F, Roncucci P

机构信息

I UO di Anestesia e Rianimazione, USL n. 13-Spedali Riuniti di Livorno.

出版信息

Minerva Anestesiol. 1994 Apr;60(4):195-201.

PMID:8090318
Abstract

The authors report the results of a survey on M. H. in Tuscany during five years from 1986 to 1990, in order to ascertain frequency, to point out the system of evaluation of the reported cases, to pick out risk-subjects, to find out the presence of dantrolene in various hospitals and to contribute to the surveys held all over the nation. That is the reason why all the persons responsible for Anaesthesiology Depts. and their collaborators were interested in this survey, through a questionnaire which, where necessary, was further developed. The great number of participants, who supplied their data, allowed is to establish trustworthy values of the set objectives. The number of MH cases was coincident with national and international data: the necessity emerged of an only collecting center and of a sale system of classification of data in order to record and compare them in an homogenous way. Detection of subjects was made possible, in most cases, by personal and familiar anamnesis, and it allowed the very few suspect cases to be sent to the specific centers. We recommend that dantrolene, even though present in most hospitals, be available more widespreadly.

摘要

作者报告了1986年至1990年这五年间在托斯卡纳对恶性高热(M. H.)进行的一项调查结果,目的是确定其发生率,指出报告病例的评估体系,找出高危人群,查明各医院丹曲林的储备情况,并为全国范围内开展的调查提供资料。这就是为什么所有麻醉科负责人及其合作者都对这项调查感兴趣,他们通过一份必要时会进一步完善的调查问卷来参与。大量参与者提供了他们的数据,这使我们能够确定既定目标的可靠数值。恶性高热病例的数量与国内和国际数据一致:由此产生了设立单一收集中心以及统一数据分类系统的必要性,以便以统一的方式记录和比较这些数据。在大多数情况下,通过个人及家族病史得以发现相关病例,并将极少数疑似病例送往特定中心。我们建议,尽管大多数医院都有丹曲林,但应使其更广泛可得。

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