Tavakkoli H, Sugar J
Pannu Eye Institute, Lauderdale Lake, Fla.
Ophthalmic Surg. 1994 Jun;25(6):356-60.
A retrospective study of 36 cases of infectious keratitis in the graft following 885 consecutive penetrating keratoplasties was conducted to evaluate the spectrum of pathogens and the factors affecting graft survival. Gram positive cocci and gram negative rods were equally responsible (47% in both cases) for 94% of the infections. Epithelial defects were responsible for 64% of the ulcers; suture-related infections, for 36%. After the infectious keratitis resolved, only 50% of the patients had a clear graft. Because the visual prognosis is poor once infectious keratitis develops, aggressive treatment is essential as soon as any sign of infiltration appears.
对885例连续穿透性角膜移植术后发生的36例移植后感染性角膜炎进行回顾性研究，以评估病原体谱及影响移植存活的因素。革兰氏阳性球菌和革兰氏阴性杆菌在94%的感染中所占比例相同（均为47%）。上皮缺损导致64%的溃疡；缝线相关感染导致36%的溃疡。感染性角膜炎消退后，只有50%的患者移植角膜保持透明。由于一旦发生感染性角膜炎，视力预后较差，因此一旦出现任何浸润迹象，积极治疗至关重要。
