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[重组人促红细胞生成素治疗持续性非卧床腹膜透析儿童尿毒症贫血]

[Human recombinant erythropoietin in treatment of uremic anemia in children with continual ambulatory peritoneal dialysis].

作者信息

Litwin M, Boguszewska-Baczkowska A, Jelonek A

机构信息

Oddziału Dializoterapii i Transpalntacji Nerek Centrum Zdrowia Dziecka.

出版信息

Pol Tyg Lek. 1994;49(6-7):135-6.

PMID:8090665
Abstract

Human recombinant erythropoietin has been administered to 6 children with uremic anaemia in the course of end stage renal disease, treated with CAPD. The drug has been injected subcutaneously in the dose of 2,000 U twice a week, until hematocrit and hemoglobin values equivalent to 30% and 9-10 g/dL have been achieved. A decrease in cytotoxic antibodies titre has been noted during a 6-month follow-up. No serious adverse reactions have been seen.

摘要

已对6名患有终末期肾病尿毒症贫血且接受持续性非卧床腹膜透析(CAPD)治疗的儿童使用了人重组促红细胞生成素。该药物以每周两次、每次2000单位的剂量皮下注射,直至血细胞比容和血红蛋白值分别达到30%和9 - 10 g/dL。在6个月的随访期间,观察到细胞毒性抗体滴度有所下降。未发现严重不良反应。

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1
[Human recombinant erythropoietin in treatment of uremic anemia in children with continual ambulatory peritoneal dialysis].[重组人促红细胞生成素治疗持续性非卧床腹膜透析儿童尿毒症贫血]
Pol Tyg Lek. 1994;49(6-7):135-6.
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[Results of treating uremia anemia with human recombinant erythropoietin].[用人重组促红细胞生成素治疗尿毒症贫血的结果]
Pol Tyg Lek. 1994;49(6-7):132-4.
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The clinical effects of recombinant human erythropoietin for the treatment of anemia in end stage renal disease patients on dialysis.重组人促红细胞生成素治疗终末期肾病透析患者贫血的临床疗效。
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Anemia of chronic renal failure: treatment with erythropoietin.
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Correction of anemia in patients on continuous ambulatory peritoneal dialysis with subcutaneous recombinant erythropoietin twice a week: a long-term study.
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Subcutaneous recombinant human erythropoietin in patients on CAPD.持续性非卧床腹膜透析患者皮下注射重组人促红细胞生成素
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8
Once weekly subcutaneous administration of recombinant erythropoietin in children treated with CAPD.接受持续性非卧床腹膜透析治疗的儿童中,重组促红细胞生成素每周一次皮下给药。
Adv Perit Dial. 1992;8:440-3.
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[Effectiveness of and tolerance to human recombinant erythropoietin in the treatment of kidney failure anemia in children undergoing continuous peritoneal dialysis. Multicenter study].
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Treatment of the anemia with human recombinant erythropoietin in CAPD patients.在持续性非卧床腹膜透析(CAPD)患者中用人重组促红细胞生成素治疗贫血。
Adv Perit Dial. 1990;6:296-301.