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[重组人促红细胞生成素治疗持续性非卧床腹膜透析儿童尿毒症贫血]

[Human recombinant erythropoietin in treatment of uremic anemia in children with continual ambulatory peritoneal dialysis].

作者信息

Litwin M, Boguszewska-Baczkowska A, Jelonek A

机构信息

Oddziału Dializoterapii i Transpalntacji Nerek Centrum Zdrowia Dziecka.

出版信息

Pol Tyg Lek. 1994;49(6-7):135-6.

PMID:8090665
Abstract

Human recombinant erythropoietin has been administered to 6 children with uremic anaemia in the course of end stage renal disease, treated with CAPD. The drug has been injected subcutaneously in the dose of 2,000 U twice a week, until hematocrit and hemoglobin values equivalent to 30% and 9-10 g/dL have been achieved. A decrease in cytotoxic antibodies titre has been noted during a 6-month follow-up. No serious adverse reactions have been seen.

摘要

已对6名患有终末期肾病尿毒症贫血且接受持续性非卧床腹膜透析(CAPD)治疗的儿童使用了人重组促红细胞生成素。该药物以每周两次、每次2000单位的剂量皮下注射,直至血细胞比容和血红蛋白值分别达到30%和9 - 10 g/dL。在6个月的随访期间,观察到细胞毒性抗体滴度有所下降。未发现严重不良反应。

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