Kurino M, Kuratsu J, Yamaguchi T, Ushio Y
Department of Neurosurgery, Kumamoto University Medical School, Japan.
Surg Neurol. 1994 Aug;42(2):160-4. doi: 10.1016/0090-3019(94)90378-6.
Solid granulomas and aneurysms caused by Aspergillus of the central nervous system are rare. A fungal aneurysm is usually situated proximally on the intracranial vessels and is often fatal. We report a case in which a ruptured aneurysm arose from the distal portion of the left posterior inferior cerebellar artery (PICA) in the course of treatment for chronic meningitis forming a granuloma at the left pyramis. After biopsy of the granuloma, he presented subarachnoid hemorrhage caused by a saccular PICA aneurysm. Histologic examination of the aneurysmal wall and the granuloma revealed infection with Aspergillus hyphae. The literature regarding the management of aspergillotic aneurysm is reviewed.
由曲霉菌引起的中枢神经系统实性肉芽肿和动脉瘤较为罕见。真菌性动脉瘤通常位于颅内血管近端,往往是致命的。我们报告一例,在慢性脑膜炎治疗过程中,左侧小脑下后动脉(PICA)远端形成肉芽肿,随后该部位出现破裂动脉瘤,该动脉瘤位于左侧锥体。肉芽肿活检后,患者出现囊状PICA动脉瘤导致的蛛网膜下腔出血。对动脉瘤壁和肉芽肿进行组织学检查,发现有曲霉菌丝感染。本文对曲霉菌性动脉瘤的治疗相关文献进行了综述。