Petrosian E A
Vestn Khir Im I I Grek. 1993 May-Jun;150(5-6):18-21.
The method of indirect electrochemical oxidation was used in treatment of 34 patients with acute purulent peritonitis. Twenty patients treated by the traditional method were taken as a group of comparison. The method consists in the elevation of sensitivity of the polyresistant microflora to antibiotics after the introduction into the abdominal cavity of a warmed to 37 degrees C 0.06--0.08% solution of sodium hypochlorite (100-400 ml), buffered with sodium bicarbonate 0.4 g NaHO3 per 100 ml. A combined application of buffered sodium hypochlorite with antibiotics to patients with local, diffuse and general peritonitis resulted in shorter average terms of treatment correspondingly to (9 +/- 0.9), (13 +/- 1.3), (16 +/- 1.9) days against (17.2 +/- 2.4), (25.0 +/- 3.3), (34.7 +/- 4.1) days after traditional methods of treatment. Only 2 patients died of 13 patients with general peritonitis (15.38%). Thus, modelling the processes of oxidative detoxication and phagocytosis with using a transmitter of acute oxygen--an electrolysis solution of sodium hypochlorite is a practically safe and technically simple method of the active action on the inflammatory process in the abdominal cavity, so it may be widely used in treatment of peritonitis.
采用间接电化学氧化法治疗34例急性化脓性腹膜炎患者。将20例采用传统方法治疗的患者作为对照组。该方法是将加热至37℃的0.06 - 0.08%次氯酸钠溶液（100 - 400 ml）注入腹腔，该溶液用每100 ml含0.4 g碳酸氢钠缓冲，可提高多重耐药微生物对抗生素的敏感性。对局部、弥漫性和全身性腹膜炎患者联合应用缓冲次氯酸钠和抗生素，其平均治疗时间相应缩短至（9±0.9）、（13±1.3）、（16±1.9）天，而传统治疗方法后的平均治疗时间为（17.2±2.4）、（25.0±3.3）、（34.7±4.1）天。在13例全身性腹膜炎患者中，仅2例死亡（15.38%）。因此，利用急性氧的传递体——次氯酸钠电解溶液模拟氧化解毒和吞噬过程，是一种对腹腔内炎症过程进行积极作用的实际安全且技术简单的方法，可广泛应用于腹膜炎的治疗。
