Hörmann C, Benzer H
Klinik für Anästhesie und Allgemeine Intensivmedizin, Universität Innsbruck.
Wien Klin Wochenschr. 1994;106(13):407-11.
In spontaneous breathing intrathoracic pressure alternates between positive and negative in a biphasic sequential pattern. By contrast, during mechanical ventilation (IPPV, CPPV) the intrathoracic pressure remains above atmospheric all the time. Due to these unphysiological conditions there are extensive causal and side effects on the lung parenchyma and other organs. Errors in the artificial ventilation technique can magnify these effects. In order to minimize these deleterious effects of positive pressure ventilation it is essential to keep the procedure as short and little invasive as possible. The following strategy enables this goal to be brought closer: 1) early commencement of ventilation; 2) optimal adjustment of artificial ventilation to the individual needs of the patient, 3) early weaning from assisted ventilation through augmented rather than controlled modes of ventilation: 4) kinetic therapy (systematic changing of the patient's position) with the back up of the requisite thoracic CT scan findings; 5) reduction of the invasiveness of the procedure in order to ensure early commencement of spontaneous respiration.
在自主呼吸时,胸腔内压力以双相顺序模式在正负之间交替。相比之下,在机械通气(间歇正压通气、持续正压通气)过程中,胸腔内压力始终高于大气压。由于这些非生理状态,对肺实质和其他器官会产生广泛的因果关系和副作用。人工通气技术中的错误会放大这些影响。为了尽量减少正压通气的这些有害影响,必须使该过程尽可能简短且侵入性小。以下策略有助于实现这一目标:1)尽早开始通气;2)根据患者的个体需求对人工通气进行最佳调整;3)通过增强而非控制通气模式尽早从辅助通气中撤机;4)在必要的胸部CT扫描结果支持下进行动态治疗(系统改变患者体位);5)降低该操作的侵入性,以确保尽早开始自主呼吸。