Stefos G
Laboratoire du Sommeil, Cliniques Universitaires de Bruxelles, Hôpital Erasme.
Acta Psychiatr Belg. 1993;93 Spec No:311-21.
In a retrospective study, the sleep EEG profiles and the neuroendocrine variables of 44 delusional and 44 non-delusional depressive matched for age, sex, and polarity were compared. Some classical biological disturbances in depressives patients (increase of awake duration, diminished REM latency, hypercortisolism, blunted TSH response) seemed to be more pronounced in the psychotic depressed group; nevertheless, they could be attributable to a greater severity. However, shortened REM latency seemed to be more specific to the psychotic subtype of depression.
在一项回顾性研究中,对44名妄想型和44名非妄想型抑郁症患者的睡眠脑电图特征及神经内分泌变量进行了比较,这些患者在年龄、性别和抑郁极性方面相互匹配。抑郁症患者的一些典型生物学紊乱(清醒时间增加、快速眼动睡眠潜伏期缩短、高皮质醇血症、促甲状腺激素反应迟钝)在精神病性抑郁组中似乎更为明显;然而,它们可能归因于病情更严重。不过,快速眼动睡眠潜伏期缩短似乎对抑郁的精神病性亚型更具特异性。