Talarmin F, Hugard L, Mion M, Sellier P, Charles D
Service de Médecine Interne et Oncologie Médicale, Hôpital Principal de Dakar, Sénégal.
Ann Med Interne (Paris). 1994;145(3):159-62.
Eight patients with vitamin deficiency pancytopenia were admitted, within a year, in a department of internal medicine. Folic acid and vitamin B12 metabolism and the clinical and haematological symptoms are discussed. These vitamin deficiencies are frequent in underdeveloped countries and are responsible of megaloblastic anaemia. Such deficiencies may also influence the granulocyte and platelet lines and may be mistaken for leukaemia. A therapeutic test may be undertaken, giving rapid diagnosis and avoiding high mortality.
一年内,有8名维生素缺乏性全血细胞减少症患者入住了内科某科室。本文讨论了叶酸和维生素B12的代谢以及临床和血液学症状。这些维生素缺乏症在不发达国家很常见,是巨幼细胞贫血的病因。此类缺乏症也可能影响粒细胞和血小板系,可能被误诊为白血病。可以进行治疗性试验,从而快速诊断并避免高死亡率。