Krisman C R, Barengo R
Eur J Biochem. 1975 Mar 3;52(1):117-23. doi: 10.1111/j.1432-1033.1975.tb03979.x.
The mechanism of glycogen biosynthesis in the absence of added primers takes place at least in two different steps. The first step could be initiated by a new enzyme named glycogen intiator synthase that catalyzes the transfer of glucose from UDP-glucose to an acceptor protein. This step takes place in vitro only in the presence of some salts at high concentration. The complex product from this reaction has been isolated and demonstrated to act as a precursor for the synthesis of glycogen which takes place in the second step and is catalyzed by the already known glycogen synthase.
在没有添加引物的情况下，糖原生物合成机制至少分两个不同步骤进行。第一步可能由一种名为糖原起始合成酶的新酶启动，该酶催化葡萄糖从尿苷二磷酸葡萄糖转移到一种受体蛋白上。这一步仅在高浓度的某些盐存在下于体外发生。已分离出该反应的复合产物，并证明其可作为糖原合成的前体，糖原合成在第二步进行，由已知的糖原合酶催化。
