影响极早产儿3年生存率及预后的因素。
Factors affecting survival and outcome at 3 years in extremely preterm infants.
作者信息
Cooke R W
机构信息
Department of Child Health, University of Liverpool.
出版信息
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F28-31. doi: 10.1136/fn.71.1.f28.
Abstract
A total of 823 infants born at 28 weeks' gestation or less were admitted to a regional referral unit between 1980 and 1989. Four hundred and sixty five (56.5%) survived to be discharged home. Twenty one subsequently died and two were lost to follow up. Four hundred and forty two (53.7%) were assessed for disabilities at the age of 3 years. Eighty four (19%) had major disabilities, of which 40 (9%) were severe. A further 39 (9%) had lesser disabilities. Three hundred and nineteen (63%) survivors appeared to be functioning normally. Logistic regression showed the likelihood of survival to be independently related to gestational age, birthweight ratio, and more recent year of birth, and inversely related to male sex and ultrasound evidence of cerebral haemorrhage or infarction. The likelihood of later disability in survivors was only independently related to cerebral ultrasound appearances.
摘要
1980年至1989年间，共有823名孕周28周及以下的婴儿被收治于一家区域转诊单位。其中465名（56.5%）存活至出院回家。21名随后死亡，2名失访。442名（53.7%）在3岁时接受了残疾评估。84名（19%）有严重残疾，其中40名（9%）为重度残疾。另有39名（9%）有较轻残疾。319名（63%）存活者似乎功能正常。逻辑回归分析显示，存活的可能性与孕周、出生体重比及更近的出生年份独立相关，与男性性别以及脑内出血或梗死的超声证据呈负相关。存活者日后出现残疾的可能性仅与脑部超声表现独立相关。
相似文献
1
Factors affecting survival and outcome at 3 years in extremely preterm infants.影响极早产儿3年生存率及预后的因素。
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F28-31. doi: 10.1136/fn.71.1.f28.
2
Outcome at 2 years of children 23-27 weeks' gestation born in Victoria in 1991-92. The Victorian Infant Collaborative Study Group.1991 - 1992年在维多利亚州出生的妊娠23 - 27周儿童的2年随访结果。维多利亚州婴儿协作研究小组。
J Paediatr Child Health. 1997 Apr;33(2):161-5.
3
Neurodevelopmental outcome in extremely preterm infants at 2.5 years after active perinatal care in Sweden.瑞典积极围产期护理后极低出生体重儿 2.5 岁时的神经发育结局。
JAMA. 2013 May 1;309(17):1810-20. doi: 10.1001/jama.2013.3786.
4
Effect of neonatal periventricular haemorrhage on neurodevelopmental outcome.新生儿脑室周围出血对神经发育结局的影响。
Arch Dis Child. 1985 Jan;60(1):8-11. doi: 10.1136/adc.60.1.8.
5
Impact of obstetric factors on outcome of extremely preterm births in Sweden: prospective population-based observational study (EXPRESS).产科因素对瑞典极早早产结局的影响：基于人群的前瞻性观察研究（EXPRESS）
Acta Obstet Gynecol Scand. 2015 Nov;94(11):1203-14. doi: 10.1111/aogs.12726. Epub 2015 Sep 7.
6
Improved outcome for infants at the limits of viability.
Eur J Pediatr. 1996 Aug;155(8):665-7. doi: 10.1007/BF01957149.
7
Pregnancy outcome at 24-31 weeks' gestation: neonatal survivors.妊娠24至31周时的妊娠结局：新生儿存活者。
Arch Dis Child. 1989 May;64(5):678-86. doi: 10.1136/adc.64.5.678.
8
[Very premature births: Dilemmas and management. Part 1. Outcome of infants born before 28 weeks of postmenstrual age, and definition of a gray zone].[极早早产：困境与管理。第1部分。月经龄28周前出生婴儿的结局及灰色地带的定义]
Arch Pediatr. 2010 May;17(5):518-26. doi: 10.1016/j.arcped.2009.09.025. Epub 2010 Mar 12.
9
Beyond the borderline: outcomes for inborn infants born at ≤500 grams.超越临界值：出生体重≤500克的早产儿的结局
J Paediatr Child Health. 2014 Feb;50(2):146-52. doi: 10.1111/jpc.12414. Epub 2013 Oct 6.
10
Infants with gestational age 28 weeks or less.孕龄28周及以下的婴儿。
Dan Med Bull. 1996 Feb;43(1):86-91.
引用本文的文献
1
Fetal programming and early identification of newborns at high risk of free radical-mediated diseases.胎儿编程与自由基介导疾病高危新生儿的早期识别
World J Clin Pediatr. 2016 May 8;5(2):172-81. doi: 10.5409/wjcp.v5.i2.172.
2
Birth weight independently affects morbidity and mortality of extremely preterm neonates.出生体重独立影响极早产儿的发病率和死亡率。
J Clin Med Res. 2015 Jul;7(7):511-6. doi: 10.14740/jocmr2075w. Epub 2015 May 8.
3
Children born weighing less than 1701 g: visual and cognitive outcomes at 11-14 years.出生体重低于1701克的儿童：11至14岁时的视觉和认知结果。
Arch Dis Child Fetal Neonatal Ed. 2007 Jul;92(4):F265-70. doi: 10.1136/adc.2006.104000. Epub 2007 Feb 16.
4
A national two year follow up study of extremely low birthweight infants born in 1996-1997.一项针对1996年至1997年出生的极低出生体重儿的全国性两年随访研究。
Arch Dis Child Fetal Neonatal Ed. 2003 Jan;88(1):F29-35. doi: 10.1136/fn.88.1.f29.
5
The Health Status Questionnaire: achieving concordance with published disability criteria.健康状况问卷：与已发布的残疾标准达成一致
Arch Dis Child. 2002 Jan;86(1):15-20. doi: 10.1136/adc.86.1.15.
6
Improved survival and neurodevelopmental outcome after prolonged ventilation in preterm neonates who have received antenatal steroids and surfactant.接受产前类固醇和表面活性剂治疗的早产儿长时间通气后生存及神经发育结局得到改善。
Arch Dis Child Fetal Neonatal Ed. 2001 May;84(3):F194-6. doi: 10.1136/fn.84.3.f194.
7
Evidence of selection bias in preterm survival studies: a systematic review.早产生存研究中选择偏倚的证据：一项系统综述。
Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F79-84. doi: 10.1136/fn.84.2.f79.
8
Antioxidant activity, packed cell transfusions, and outcome in premature infants.抗氧化活性、红细胞压积输血与早产儿的预后
Arch Dis Child Fetal Neonatal Ed. 1998 May;78(3):F214-9. doi: 10.1136/fn.78.3.f214.
9
Increased survival and deteriorating developmental outcome in 23 to 25 week old gestation infants, 1990-4 compared with 1984-9.与1984 - 1989年相比，1990 - 1994年孕龄23至25周婴儿的存活率提高但发育结局恶化。
Arch Dis Child Fetal Neonatal Ed. 1998 Mar;78(2):F99-104. doi: 10.1136/fn.78.2.f99.
10
Children conceived by in vitro fertilisation after fresh embryo transfer.新鲜胚胎移植后通过体外受精受孕的儿童。
Arch Dis Child Fetal Neonatal Ed. 1997 Mar;76(2):F70-4. doi: 10.1136/fn.76.2.f70.
本文引用的文献
1
Outcome at 8 years for children with birth weights of 1250 g or less.出生体重1250克及以下儿童8岁时的结局。
Arch Dis Child. 1993 Mar;68(3 Spec No):286-90. doi: 10.1136/adc.68.3_spec_no.286.
2
Annual audit of three year outcome in very low birthweight infants.极低出生体重儿三年结局的年度审计
Arch Dis Child. 1993 Sep;69(3 Spec No):295-8. doi: 10.1136/adc.69.3_spec_no.295.
3
How aggressive should delivery room cardiopulmonary resuscitation be for extremely low birth weight neonates?
Pediatrics. 1993 Sep;92(3):447-50.
4
Functional abilities at age 4 years of children born before 29 weeks of gestation.
BMJ. 1993 Jun 26;306(6894):1715-8. doi: 10.1136/bmj.306.6894.1715.
5
Epidemiology of birth before 28 weeks of gestation.
Br Med Bull. 1988 Oct;44(4):861-93. doi: 10.1093/oxfordjournals.bmb.a072298.
6
Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress.吸烟、饮酒、咖啡因、社会经济因素及心理社会压力对出生体重的影响。
BMJ. 1989 Mar 25;298(6676):795-801. doi: 10.1136/bmj.298.6676.795.
7
Motor skills in extremely low birthweight children at the age of 6 years.极低出生体重儿6岁时的运动技能
Arch Dis Child. 1989 Jun;64(6):839-47. doi: 10.1136/adc.64.6.839.
8
Costs and benefits of neonatal intensive care.
Arch Dis Child. 1988 Jul;63(7 Spec No):715-8. doi: 10.1136/adc.63.7_spec_no.715.
9
Early and late cranial ultrasonographic appearances and outcome in very low birthweight infants.极低出生体重儿的早晚期头颅超声表现及预后
Arch Dis Child. 1987 Sep;62(9):931-7. doi: 10.1136/adc.62.9.931.
10
Prognosis for infants born at 23 to 28 weeks' gestation.孕23至28周出生婴儿的预后。
Br Med J (Clin Res Ed). 1986 Nov 8;293(6556):1200-3. doi: 10.1136/bmj.293.6556.1200.
Zotero 插件