Orekhov O O, Kapuller L L, Vorob'ev G I, Achkasov S I, Zarodniuk I V
Arkh Patol. 1994 May-Jun;56(3):30-5.
Two clinico-morphological forms of colon diverticulosis are distinguished on the basis of post-mortem and surgical material (89 observations) studied histologically, neurohistologically and electron-microscopically. The first form is characterized by the disturbance of colon peristalsis, inflammation, segmentation of the colon wall and the presence of staged changes in the colon wall muscles. Disturbances of the vegetative innervation and regional hemodynamic disturbances play a role in the patho- and morphogenesis. The second form develops in aged persons and is characterized by weakness of the colon wall with thinning of the muscle layer. In both forms atrophy of the circular muscle layer develops with dilation of perivascular spaces and formation of "weak sites" in the colonic wall.
根据对89例尸检和手术材料进行组织学、神经组织学及电子显微镜研究，区分出结肠憩室病的两种临床形态学类型。第一种类型的特征是结肠蠕动紊乱、炎症、结肠壁节段性改变以及结肠壁肌肉存在分期变化。自主神经支配紊乱和局部血流动力学紊乱在发病机制和形态发生中起作用。第二种类型发生于老年人，其特征是结肠壁薄弱，肌层变薄。在这两种类型中，环形肌层均发生萎缩，血管周围间隙扩张，结肠壁形成“薄弱部位”。
