Ryuko K, Iwanari O, Abu-Musa A, Fujiwaki R, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
Asia Oceania J Obstet Gynaecol. 1994 Jun;20(2):135-40. doi: 10.1111/j.1447-0756.1994.tb00439.x.
The first reported case of cerebellar metastasis from primary clear cell adenocarcinoma of the fallopian tube is presented. Initially diagnosed as stage Ia, the patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and omentectomy, followed by cisplatin-based chemotherapy and whole pelvic irradiation. Thirty six months later multiple pulmonary metastases were detected that did not respond to chemotherapy. Later the patient presented with cerebellar metastasis. She received whole brain radiotherapy and steroids. The brain lesion partially responded and the patient's neurologic symptoms improved. Throughout there was no evidence of local recurrence. This case suggests that with the prolonged survival achieved by aggressive treatment occult brain metastases might become apparent.
本文报道了首例原发性输卵管透明细胞腺癌小脑转移病例。该患者最初诊断为Ia期，接受了全腹子宫切除术、双侧输卵管卵巢切除术和大网膜切除术，随后进行了以顺铂为基础的化疗和全盆腔放疗。36个月后，发现多处肺转移，化疗无效。后来患者出现小脑转移。她接受了全脑放疗和类固醇治疗。脑部病变部分缓解，患者的神经症状有所改善。自始至终均无局部复发的证据。该病例表明，通过积极治疗延长生存期后，隐匿性脑转移可能会显现出来。
