选择性D1和D2激动剂在初治MPTP猴诱发运动障碍中的作用。 - Suppr

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超能文献

Role of selective D1 and D2 agonists in inducing dyskinesia in drug-naive MPTP monkeys.

作者信息

Bédard P J, Gomez-Mancilla B, Blanchette P, Gagnon C, Falardeau P, DiPaolo T

机构信息

Centre de Recherche en Neurobiologie, Hôpital de l'Enfant-Jésus, (Qc), Canada.

出版信息

Adv Neurol. 1993;60:113-8.

PMID:8093573

Abstract

摘要

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Role of selective D1 and D2 agonists in inducing dyskinesia in drug-naive MPTP monkeys.选择性D1和D2激动剂在初治MPTP猴诱发运动障碍中的作用。

Adv Neurol. 1993;60:113-8.

The effects of D1 and D2 dopamine receptor agonist and antagonist on parkinsonism in chronic MPTP-treated monkeys.D1和D2多巴胺受体激动剂及拮抗剂对慢性MPTP处理的猴子帕金森症的影响。

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Dyskinesia and wearing-off following dopamine D1 agonist treatment in drug-naive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates.多巴胺D1激动剂治疗初治的1-甲基-4-苯基-1,2,3,6-四氢吡啶损伤灵长类动物后的运动障碍和药效减退。

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Changes of D1 and D2 dopamine receptor mRNA in the brains of monkeys lesioned with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correction with chronic administration of L-3,4-dihydroxyphenylalanine.1-甲基-4-苯基-1,2,3,6-四氢吡啶损伤的猴子大脑中多巴胺D1和D2受体mRNA的变化：长期给予L-3,4-二羟基苯丙氨酸的校正作用

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De novo administration of ropinirole and bromocriptine induces less dyskinesia than L-dopa in the MPTP-treated marmoset.在经MPTP处理的狨猴中，与左旋多巴相比，罗匹尼罗和溴隐亭的从头给药诱导的运动障碍较少。

Mov Disord. 1998 Mar;13(2):234-41. doi: 10.1002/mds.870130207.

The effects of chronic levodopa treatment on pre- and postsynaptic markers of dopaminergic function in striatum of parkinsonian monkeys.慢性左旋多巴治疗对帕金森病猴纹状体中多巴胺能功能的突触前和突触后标志物的影响。

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Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys.选择性D-1和D-2多巴胺受体激动剂对1-甲基-4-苯基-1,2,3,6-四氢吡啶处理的猴子左旋多巴诱发异动症的差异作用。

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N-methyl-D-aspartate receptor antagonist and dopamine D1 and D2 agonist interactions in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced hemiparkinsonian monkeys.N-甲基-D-天冬氨酸受体拮抗剂与多巴胺D1和D2激动剂在1-甲基-4-苯基-1,2,5,6-四氢吡啶诱导的偏侧帕金森病猴中的相互作用

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Effect of adding the D1 agonist CY 208-243 to chronic bromocriptine treatment. I: Evaluation of motor parameters in relation to striatal catecholamine content and dopamine receptors.在慢性溴隐亭治疗中添加D1激动剂CY 208-243的效果。I：与纹状体儿茶酚胺含量和多巴胺受体相关的运动参数评估。

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DOPA-induced "peak dose" dyskinesia: clues implicating D2 receptor-mediated mechanisms using dopaminergic agonists in MPTP monkeys.左旋多巴诱发的“峰值剂量”异动症：在MPTP猴中使用多巴胺能激动剂暗示D2受体介导机制的线索

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Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors.左旋多巴诱导的异动症大鼠模型中纹状体细胞外信号调节激酶1/2磷酸化的时空模式及多巴胺D1受体的作用

Biol Psychiatry. 2007 Oct 1;62(7):800-10. doi: 10.1016/j.biopsych.2006.11.032. Epub 2007 Jul 26.

Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys.局部纹状体多巴胺可能会增强帕金森病猴的运动障碍。

Exp Neurol. 2006 Feb;197(2):363-72. doi: 10.1016/j.expneurol.2005.10.022. Epub 2005 Dec 9.

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J Neural Transm (Vienna). 1997;104(4-5):341-62. doi: 10.1007/BF01277656.

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