Macía M, Novo A, Ces J, González M, Quintana S, Codesido J
Department of Gynecology and Obstetrics, Hospital General de Galicia, Facultad de Medicina, Santiago de Compostela, Spain.
Int J Gynaecol Obstet. 1993 Feb;40(2):145-9. doi: 10.1016/0020-7292(93)90375-7.
The progesterone challenge test was correlated with endometrial pathology in 130 asymptomatic menopausal women without hormonal treatment. The sensitivity of the test for detection of endometrial proliferative activity was 76%, specificity 100%, positive predictive value 100% and negative predictive value 94.1%. A 10-day test provided better results than a 5-day test. The test seems useful for detection of those at high risk for endometrial cancer.