抗CD18和抗CD11a单克隆抗体对大鼠心脏同种异体移植的免疫抑制作用比较 - Suppr | 超能文献

Comparative immunosuppressive effect of anti-CD18 and anti-CD11a monoclonal antibodies on rat heart allotransplantation.

作者信息

Kameoka H, Ishibashi M, Tamatani T, Takano Y, Moutabarrik A, Jiang H, Kokado Y, Takahara S, Miyasaka M, Okuyama A

机构信息

Department of Urology, Osaka University Hospital, Japan.

出版信息

Transplant Proc. 1993 Feb;25(1 Pt 1):833-6.

Abstract

摘要

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Comparative immunosuppressive effect of anti-CD18 and anti-CD11a monoclonal antibodies on rat heart allotransplantation.抗CD18和抗CD11a单克隆抗体对大鼠心脏同种异体移植的免疫抑制作用比较

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A non-lymphocyte-depleting monoclonal antibody to the adhesion molecule LFA-1 (CD11a) prevents sensitization to alloantigens and effectively prolongs the survival of heart allografts.一种针对黏附分子淋巴细胞功能相关抗原-1（CD11a）的非淋巴细胞清除性单克隆抗体可防止对同种异体抗原产生致敏，并有效延长心脏同种异体移植的存活时间。

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