Al-Dujaili A H, Harris D M
J Hyg (Lond). 1975 Oct;75(2):195-201. doi: 10.1017/s0022172400047227.
One hundred and fifty-six infections or episodes of infection associated with Pseudomonas aeruginosa in six hospitals over 14 months were investigated. Pyocine typing and serotyping suggested that 145 distinct episodes had occurred, caused by 78 different strains. During this period 15 distinct strains were isolated from the environment at one of the hospitals; 12 of these were apparently unassociated with infection in the same ward during the period, and 4 were of types not encountered in infective processes at any hospital. There appeared to be a rather higher proportion of unclassifiable pyocine inhibition patterns among the environmental strains; in general these strains also produced smaller amounts of haemolysin. If failure to produce haemolysin in vitro is correlated with lack of virulence in vivo, this may partially explain the sporadic nature of hospital infection with Ps. aeruginosa, despite the prevalence of strains of this species in the environment.
对六家医院在14个月内发生的156例与铜绿假单胞菌相关的感染或感染事件进行了调查。荧光素分型和血清分型表明，共发生了145起不同的感染事件，由78种不同菌株引起。在此期间，从其中一家医院的环境中分离出15种不同的菌株；其中12种在此期间显然与同一病房的感染无关，4种的类型在任何医院的感染过程中均未见过。环境菌株中似乎有相当高比例的无法分类的荧光素抑制模式；总体而言，这些菌株产生的溶血素量也较少。如果体外不产生溶血素与体内缺乏毒力相关，这可能部分解释了铜绿假单胞菌医院感染的散发性，尽管该菌在环境中普遍存在。
