Scott G R, Rothkopf D M, Walton R L
Division of Plastic and Reconstructive Surgery, University of Massachusetts Medical Center, Worcester.
Plast Reconstr Surg. 1993 Apr;91(4):673-7. doi: 10.1097/00006534-199304000-00016.
Epidural anesthesia is an effective means of providing pain control and chemical sympathectomy at the spinal nerve root level. The purpose of this study is to compare the efficacy of the combination of epidural and general anesthesia to general anesthesia alone in patients undergoing free flaps to the lower extremity. A retrospective review of 35 consecutive patients (36 operations) from November of 1988 to November of 1990 undergoing free tissue transfer to the lower extremity was undertaken. Sixteen patients had epidural and general anesthesia, and 19 (20 operations) had general anesthesia alone. There were no significant differences in the age or sex of the patients, the distribution between acute and chronic wounds, or the number of cigarette smokers in the two groups. There were no flap losses in the epidural group (100 percent success) and one major, but nonmicrovascular complication (6 percent). In the nonepidural group, there were one flap loss (95 percent success) and five major complications (25 percent). These included three microvascular complications (15 percent). There were significantly fewer patients with postoperative atelectatic fevers in the epidural group versus the nonepidural group. In this consecutive series of patients, epidural supplementation of general anesthesia for free flaps to the lower extremity was associated with uniformly successful flap survival and a lower rate of microvascular complications compared to general anesthesia alone.
硬膜外麻醉是在脊神经根水平提供疼痛控制和化学性交感神经切除术的有效手段。本研究的目的是比较硬膜外麻醉与全身麻醉联合应用与单纯全身麻醉在接受下肢游离皮瓣手术患者中的疗效。对1988年11月至1990年11月连续35例(36次手术)接受下肢游离组织移植的患者进行了回顾性研究。16例患者接受了硬膜外麻醉与全身麻醉联合应用,19例(20次手术)仅接受全身麻醉。两组患者的年龄、性别、急性和慢性伤口分布或吸烟者数量均无显著差异。硬膜外麻醉组无皮瓣丢失(成功率100%),有1例严重但非微血管并发症(6%)。非硬膜外麻醉组有1例皮瓣丢失(成功率95%)和5例严重并发症(25%)。其中包括3例微血管并发症(15%)。与非硬膜外麻醉组相比,硬膜外麻醉组术后肺不张发热患者明显较少。在这一系列连续患者中,与单纯全身麻醉相比,硬膜外麻醉辅助全身麻醉用于下肢游离皮瓣手术与皮瓣存活成功率一致且微血管并发症发生率较低相关。