Keller R J, Eisenbarth G S, Jackson R A
Division of Endocrinology, Children's Hospital, Boston, MA 02115.
Lancet. 1993 Apr 10;341(8850):927-8. doi: 10.1016/0140-6736(93)91215-8.
Prevention of type I diabetes is now a practical goal thanks to the ability to define confidently a high-risk group and the success of preventive strategies in animal models. We describe here a pilot trial of low-dose insulin to prevent diabetes in relatives of patients with type I diabetes.
由于能够明确界定出高风险群体，且预防性策略在动物模型中取得了成功，如今预防I型糖尿病已成为一个切实可行的目标。我们在此描述一项低剂量胰岛素预防I型糖尿病患者亲属患糖尿病的试点试验。
