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恒河猴乳汁的蛋白质组成:与人类乳汁的比较。

Protein composition of rhesus monkey milk: comparison to human milk.

作者信息

Kunz C, Lönnerdal B

机构信息

Department of Nutrition, University of California, Davis 95616.

出版信息

Comp Biochem Physiol Comp Physiol. 1993 Apr;104(4):793-7. doi: 10.1016/0300-9629(93)90156-x.

Abstract
  1. Proteins in human milk and Rhesus monkey milk have been compared by FPLC gel filtration and anion exchange chromatography, SDS-Polyacrylamide gel electrophoresis, nitrogen and protein determination. 2. Mature Rhesus milk is higher in protein concentration (15-20 mg/ml) than human milk (8-9 mg/ml). 3. Non-Protein nitrogen is 6-13% in Rhesus milk but 25-30% in human milk. 4. Secretory IgA, lactoferrin, serum albumin, alpha-lactalbumin and lysozyme are present in Rhesus milk, but at a lower concentration than in human milk. 5. The casein subunit pattern is more complex in Rhesus milk compared to human milk. 6. The ratio of whey proteins to casein is similar in both milks (approximately 60/40). 7. A protein with a M(r) of 21,600 is a major component in monkey whey but is not found in human milk.
摘要
  1. 通过快速蛋白质液相色谱凝胶过滤法、阴离子交换色谱法、十二烷基硫酸钠-聚丙烯酰胺凝胶电泳法、氮和蛋白质测定法,对人乳和恒河猴乳中的蛋白质进行了比较。2. 成熟恒河猴乳的蛋白质浓度(15 - 20毫克/毫升)高于人乳(8 - 9毫克/毫升)。3. 恒河猴乳中的非蛋白氮占6 - 13%,而人乳中的占25 - 30%。4. 恒河猴乳中存在分泌型免疫球蛋白A、乳铁蛋白、血清白蛋白、α-乳白蛋白和溶菌酶,但浓度低于人乳。5. 与母乳相比,恒河猴乳中的酪蛋白亚基模式更为复杂。6. 两种乳汁中乳清蛋白与酪蛋白的比例相似(约为60/40)。7. 一种相对分子质量为21,600的蛋白质是猴乳清中的主要成分,但在人乳中未发现。

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