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香港社会卫生诊所就诊女性的宫颈人乳头瘤病毒感染情况

Cervical human papilloma virus infection of women attending social hygiene clinics in Hong Kong.

作者信息

Ngan H Y, Collins R J, Wong K Y, Cheung A, Lai C F, Liu Y T

机构信息

Department of Obstetrics and Gynaecology, University of Hong Kong.

出版信息

Int J Gynaecol Obstet. 1993 Apr;41(1):75-9. doi: 10.1016/0020-7292(93)90157-r.

Abstract

OBJECTIVE

To find the prevalence of HPV infection in women attending a sexually transmitted disease clinic in Hong Kong.

METHOD

Cervical HPV infection was identified by cervical cytology and DNA filter in-situ-hybridization (Virapap) techniques in 207 women attending a social hygiene clinic. Other risk factors for cervical cancer were assessed and any association with HPV infection was sought. Statistical analysis was carried out using the chi 2-test.

RESULT

The prevalence of HPV infection in the 207 Chinese women was 8.2% by cervical smear and 12.6% by DNA filter in-situ-hybridization. Risk factors for cervical cancer were not significantly associated with HPV infection in this group, 95% of whom were prostitutes.

CONCLUSION

The prevalence of HPV infection in this group at high risk for cervical cancer is higher than in low-risk pregnant women, however the prevalence of HPV infection in Hong Kong is at the low end of the range of figures quoted for Caucasians. The cause of such a low prevalence is yet to be determined.

摘要

目的

探寻香港一家性传播疾病诊所就诊女性的人乳头瘤病毒(HPV)感染率。

方法

采用宫颈细胞学检查和DNA滤膜原位杂交技术(Virapap),对207名在社会卫生诊所就诊的女性进行宫颈HPV感染检测。评估宫颈癌的其他危险因素,并探寻其与HPV感染的任何关联。使用卡方检验进行统计分析。

结果

通过宫颈涂片,207名中国女性中HPV感染率为8.2%;通过DNA滤膜原位杂交技术,感染率为12.6%。该组宫颈癌危险因素与HPV感染无显著关联,其中95%为妓女。

结论

该组宫颈癌高危人群的HPV感染率高于低危孕妇,但香港的HPV感染率处于白种人所引用数据范围的低端。如此低感染率的原因尚待确定。

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