Kachadorian W A, Wade J B, DiScala V A
Science. 1975 Oct 3;190(4209):67-9. doi: 10.1126/science.809840.
Freeze-fracture electron microscopy demonstrates that vasopressin stimulation of isolated toad bladder alters the structure of the luminal membrane of granular cells. This alteration consists of an ordered aggression of intramembranous particles, and appears to be of functional significance, since the frequency of aggregation sites per area of membrane is closely correlated with vasopressin-induced osmotic water flow.
冷冻断裂电子显微镜显示,血管加压素对离体蟾蜍膀胱的刺激会改变颗粒细胞腔面膜的结构。这种改变包括膜内颗粒的有序聚集,并且似乎具有功能意义,因为每单位膜面积聚集位点的频率与血管加压素诱导的渗透水流动密切相关。