Larson S J, Sances A, Cusick J F, Meyer G A, Swiontek T
Surg Neurol. 1975 Jul;4(1):180-6.
In four patients with intractable pain from metastatic cancer, application of current through electrodes placed on the anterior surface of the cord produced analgesia and pain relief below the level of implant without the development of paresthesias. Application of current through electrodes placed on the dorsal columns in these patients also relieved pain, but to a lesser degree and with the development of associated paresthesias. In one patient, application of current from anterior electrodes to posterior electrodes produced a zone of dissociated sensory loss. While it is simpler to implant electrodes over the dorsal columns, the anterior location may be superior when currents are to be applied for the pain relief in the lower lumbar and sacral dermatomes.
在4例患有转移性癌症顽固性疼痛的患者中,通过置于脊髓前表面的电极施加电流可产生镇痛效果,且植入水平以下的疼痛得到缓解,未出现感觉异常。在这些患者中,通过置于背柱的电极施加电流也可缓解疼痛,但程度较轻且伴有相关感觉异常。在1例患者中,从前部电极向后部电极施加电流产生了感觉分离性缺失区。虽然在背柱上方植入电极更简单,但当要通过施加电流缓解下腰椎和骶部皮节的疼痛时,前部位置可能更具优势。