玛瑙螺巨型神经元对从软体动物中分离出的肽的敏感性。

Sensitivities of Achatina giant neurones to peptides isolated from mollusca.

作者信息

Liu G J, Santos D E, Takeuchi H

机构信息

Department of Physiology, Gifu University School of Medicine, Japan.

出版信息

Acta Biol Hung. 1993;44(1):25-8.

Abstract

Sensitivities of the Achatina giant neurones to the peptides isolated from Mollusca were examined by their local application of the pneumatic pressure ejection under current clamp. The peptides tested and their effects were as follows: Ser2-MIP (inhibitory). CARP (inhibitory), oxytocin (excitatory), SPCB (excitatory), alpha-BCP (no effect). ELH (no effect). APGW-amide (inhibitory) and FMRFamide (inhibitory). Membrane conductance (g) of a neurone, d-RPeAN, measured under voltage clamp, was unexpectedly decreased by SCPB during inward current (Iin) caused by the peptide.

摘要

通过在电流钳制下利用气压喷射对玛瑙螺巨型神经元进行局部施加，来检测其对从软体动物中分离出的肽的敏感性。所测试的肽及其作用如下：Ser2-MIP（抑制性）、CARP（抑制性）、催产素（兴奋性）、SPCB（兴奋性）、α-BCP（无作用）、ELH（无作用）、APGW-酰胺（抑制性）和FMRF酰胺（抑制性）。在电压钳制下测量的神经元d-RPeAN的膜电导（g），在由该肽引起的内向电流（Iin）期间，意外地被SCPB降低。

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