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Torsades de pointes and proarrhythmia.

作者信息

Ben-David J, Zipes D P

机构信息

Indiana University School of Medicine, Department of Medicine, Krannert Institute of Cardiology, Roudebush Veterans Affairs Medical Center, Indianapolis.

出版信息

Lancet. 1993 Jun 19;341(8860):1578-82. doi: 10.1016/0140-6736(93)90708-o.

DOI:10.1016/0140-6736(93)90708-o
PMID:8099651
Abstract
摘要

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Torsades de pointes and proarrhythmia.尖端扭转型室速与致心律失常作用
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Genetic basis of drug-induced arrhythmias.药物性心律失常的遗传基础。
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Understanding drug-induced torsades de pointes: a genetic stance.从遗传学角度理解药物诱发的尖端扭转型室性心动过速
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Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit.逐搏QT间期变异性而非QT间期延长本身可预测麻醉状态下甲氧明致敏兔的药物诱发尖端扭转型室速。
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Female gender does not influence the magnitude of ibutilide-induced repolarization delay and incidence of torsades de pointes in an in vivo rabbit model of the acquired long QT syndrome.在获得性长QT综合征的体内兔模型中，女性性别不影响伊布利特引起的复极延迟程度和尖端扭转型室速的发生率。
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Early afterdepolarizationlike activity in patients with class IA induced long QT syndrome and torsades de pointes.IA类药物诱发的长QT综合征和尖端扭转型室速患者早期出现类似后除极的活动。
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[Torsade de pointes and QT syndrome].[尖端扭转型室速与QT综合征]
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