Sugimoto M, Nakamura S, Hattori J, Yamada T, Horiya Y, Hara S, Shima H
Department of Internal Medicine, Gifu Red Cross Hospital, Japan.
Intern Med. 1993 Mar;32(3):266-8.
A 39-year-old woman with Graves' disease associated with follicular thyroid carcinoma underwent subtotal thyroidectomy. TSH-binding inhibitor immunoglobulins (TBII) were positive, whereas thyroid-stimulating antibodies (TSAb) and thyroid-stimulation-blocking antibodies (TSBAb) were both negative before the operation. After the operation, TBII markedly increased above the pretreatment value. TSBAb became positive 3 months after the operation and then their activity increased, while TSAb remained negative after the operation. Subtotal thyroidectomy may have influenced the development of TSBAb in this patient. Irrespective of these findings, the patient became hyperthyroid again several months after the operation.
一名患有格雷夫斯病并伴有滤泡性甲状腺癌的39岁女性接受了甲状腺次全切除术。术前促甲状腺激素结合抑制性免疫球蛋白（TBII）呈阳性，而促甲状腺激素抗体（TSAb）和促甲状腺激素阻断抗体（TSBAb）均为阴性。术后，TBII显著高于术前值。TSBAb在术后3个月转为阳性，随后其活性增加，而TSAb术后仍为阴性。甲状腺次全切除术可能影响了该患者TSBAb的产生。尽管有这些发现，患者在术后几个月再次出现甲状腺功能亢进。
