van Emmerik R E, Sprague R L, Newell K M
Faculty of Human Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
Mov Disord. 1993 Jul;8(3):305-14. doi: 10.1002/mds.870080309.
An assessment was made of the orientation and variability in postural center of pressure patterns in individuals with tardive dyskinesia (TD) and/or developmental disability during quiet standing. Postural patterns were compared and contrasted between four groups of individuals: those with (a) TD and developmentally disabled (severely and profoundly retarded); (b) developmental disability only; (c) TD but of normal intelligence; and (d) a healthy control group. The center of pressure displacements were derived from the lateral, vertical, and anterior-posterior force and moment components of force platform measurements. Analyses demonstrated that individuals with TD in combination with developmental disability had a different center of pressure orientation and variability compared to healthy individuals and individuals suffering only from developmental disability or TD. The center of pressure pattern in the developmentally disabled TD group was characterized by a more prominent lateral orientation, whereas in the other three groups, it had a more predominant anterior-posterior orientation. In addition, the variability in these orientation components was much smaller in the developmentally disabled TD group, indicating a more regular pattern of sway in the center of pressure during quiet standing in these individuals. These findings show that assessments of postural center of pressure profile orientation and variability may be useful indicators for investigating TD, especially in distinguishing between developmental disability and TD.
对患有迟发性运动障碍（TD）和/或发育障碍的个体在安静站立时压力中心模式的方向和变异性进行了评估。对四组个体的姿势模式进行了比较和对比：（a）患有TD且有发育障碍（重度和极重度智力迟缓）的个体；（b）仅患有发育障碍的个体；（c）患有TD但智力正常的个体；以及（d）健康对照组。压力中心位移来自力平台测量的横向、垂直和前后力及力矩分量。分析表明，与健康个体以及仅患有发育障碍或TD的个体相比，患有TD合并发育障碍的个体具有不同的压力中心方向和变异性。发育障碍TD组的压力中心模式的特点是横向方向更为突出，而在其他三组中，其前后方向更为显著。此外，发育障碍TD组中这些方向分量的变异性要小得多，这表明这些个体在安静站立时压力中心的摆动模式更为规律。这些发现表明，对压力中心轮廓方向和变异性的评估可能是研究TD的有用指标，尤其是在区分发育障碍和TD方面。
