Thomas R L, Haybittle J L
Br J Radiol. 1975 Sep;48(573):749-54. doi: 10.1259/0007-1285-48-573-749.
A method of computing megavoltage dose distributions using an empirical mathematical model is described. The dose at a point in a medium is calculated as the product of a central axis percentage depth dose, a crossplot factor and a wedge factor. For a given set of conditions (i.e. type of machine, source-skin distance and wedge) 16 parameters are required to calculate the values of the three factors and hence the dose at any point. These parameters can be obtained from a relatively small number of experimental measurements. Dose distributions from a variety of different treatment machines have been computed by the method, and some comparisons of the calculated and measured doses have been made using "Goodness of Fit" score values. These show that the use of the method as a basis for computer treatment planning should be clinically acceptable.
描述了一种使用经验数学模型计算兆伏级剂量分布的方法。介质中某一点的剂量计算为中心轴百分深度剂量、交叉图因子和楔形因子的乘积。对于给定的一组条件(即机器类型、源皮距离和楔形),需要16个参数来计算这三个因子的值,从而计算出任意点的剂量。这些参数可从相对少量的实验测量中获得。已通过该方法计算了各种不同治疗机器的剂量分布,并使用“拟合优度”得分值对计算剂量和测量剂量进行了一些比较。这些结果表明,将该方法用作计算机治疗计划的基础在临床上应是可接受的。