Haywood J K, Bomford C K, Hatton J A
Br J Radiol. 1979 Sep;52(621):709-18. doi: 10.1259/0007-1285-52-621-709.
A large number of initial measurements are needed for accurate computation of radiotherapy dose distributions directly from stored data on the dose distribution of single radiation beams. Because of this, interest has been shown in alternative methods which use empirical formulae to represent the dose distributions of single beams. These can be easier to implement but are less directly related to measured quantities and may be of limited validity. A method of representing radiotherapy beams is proposed which closely approximates their radiation physics, in order to calculate the dose at any point by a simple algorithm directly from a small number of initial dose measurements. The method is of wide validity, probably including all megavoltage radiations for which Compton scattering is the dominant interaction in tissue. The accuracy of the method is demonstrated by application to an 8 MV linear accelerator and a cobalt 60 machine.
为了直接从存储的单束辐射剂量分布数据准确计算放射治疗剂量分布,需要进行大量的初始测量。因此,人们对使用经验公式来表示单束剂量分布的替代方法产生了兴趣。这些方法可能更易于实施,但与测量量的直接关系较小,有效性可能有限。本文提出了一种表示放射治疗束的方法,该方法紧密逼近其辐射物理学,以便通过简单算法直接从少量初始剂量测量值计算任意点的剂量。该方法具有广泛的有效性,可能包括所有在组织中以康普顿散射为主要相互作用的兆伏级辐射。通过应用于8兆伏直线加速器和钴60机器,证明了该方法的准确性。