Cheung O T
Can Med Assoc J. 1975 Nov 8;113(9):848-9.
A review of the records of 984 patients admitted to hospital from 1970 through 1973 with bacteriologically proven pulmonary tuberculosis showed bacterial resistance to one or more antituberculosis drugs in 103 (10.5%). Among the patients who had had previous drug treatment for tuberculosis the prevalence of drug resistance was 20% in the Canadian-born patients and 69.4% in the recent immigrants. Among the patients who had had no previous drug treatment the prevalence of drug resistance (primary resistance) was 2.7% in Canadian-born patients but 11.4% in recent immigrants. Because of the higher prevalence of drug resistance among recent immigrants and the finding in recent years that increasingly more tuberculosis patients in Ontario are recent immigrants, drug resistance in this group is likely to assume even more importance in the future.
对1970年至1973年因细菌学确诊为肺结核而住院的984例患者的记录进行回顾，结果显示103例（10.5%）患者的细菌对一种或多种抗结核药物耐药。在既往接受过抗结核药物治疗的患者中，加拿大出生的患者耐药率为20%，近期移民的患者耐药率为69.4%。在既往未接受过抗结核药物治疗的患者中，加拿大出生的患者原发耐药率为2.7%，近期移民的患者原发耐药率为11.4%。由于近期移民中耐药率较高，且近年来发现安大略省越来越多的肺结核患者是近期移民，因此该群体中的耐药问题在未来可能会变得更加重要。
