Bemelman W A, Bosma A, Wiersma P H, Rauws E A, Brummelkamp W H
Department of Surgery, University of Amsterdam, Sint Lucas Hospital, The Netherlands.
Eur J Surg. 1993 Mar;159(3):171-5.
To assess the possible role of colonisation of ectopic gastric mucosa in Meckel's diverticula by Helicobacter pylori in causing inflammation, ulceration, perforation and bleeding.
Retrospective study.
Three hospitals in Amsterdam, The Netherlands.
Specimens of 65 diverticula, 49 of which had been resected incidentally, and 16 of which had been thought to be the presenting feature.
The presence of H. pylori in gastric mucosa.
19 Diverticula contained ectopic tissue, 18 gastric and one pancreatic tissue. Gastric tissue was found in 10 of the diverticula removed incidentally, and 8 of those that were thought to be symptomatic. In 5 of the 8 there were signs of complications that might have been related directly to the presence of gastric tissue (perforation--n = 3; bleeding--n = 1; and peptic stenosis--n = 1), and none contained H. pylori. H. pylori was found in only one of the 18 diverticula, in which there were also signs of gastritis.
H. pylori has no role in the pathogenesis of the complications of Meckel's diverticula.
评估幽门螺杆菌在梅克尔憩室异位胃黏膜定植中引起炎症、溃疡、穿孔和出血的可能作用。
回顾性研究。
荷兰阿姆斯特丹的三家医院。
65个憩室标本，其中49个为偶然切除，16个被认为是主要特征。
胃黏膜中幽门螺杆菌的存在情况。
19个憩室含有异位组织，18个为胃组织，1个为胰腺组织。偶然切除的10个憩室及8个有症状的憩室中发现了胃组织。8个中有5个有可能与胃组织存在直接相关的并发症迹象（穿孔——3例；出血——1例；消化性狭窄——1例），且均未发现幽门螺杆菌。18个憩室中仅1个发现幽门螺杆菌，该憩室也有胃炎迹象。
幽门螺杆菌在梅克尔憩室并发症的发病机制中不起作用。
