人类染色体7上一个基因所编码的二肽基氨基肽酶IV相关蛋白中催化残基的非保守性。 - Suppr

Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7.

作者信息

Yokotani N, Doi K, Wenthold R J, Wada K

机构信息

Laboratory of Neurochemistry, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892.

出版信息

Hum Mol Genet. 1993 Jul;2(7):1037-9. doi: 10.1093/hmg/2.7.1037.

DOI:10.1093/hmg/2.7.1037

PMID:8103397

Abstract

摘要

相似文献

Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7.人类染色体7上一个基因所编码的二肽基氨基肽酶IV相关蛋白中催化残基的非保守性。

Hum Mol Genet. 1993 Jul;2(7):1037-9. doi: 10.1093/hmg/2.7.1037.

Isolation of a cDNA probe for the human intestinal dipeptidylpeptidase IV and assignment of the gene locus DPP4 to chromosome 2.

Ann Hum Genet. 1990 Jul;54(3):191-7. doi: 10.1111/j.1469-1809.1990.tb00377.x.

Molecular cloning and sequence analysis of human dipeptidyl peptidase IV, a serine proteinase on the cell surface.人二肽基肽酶IV（一种细胞表面丝氨酸蛋白酶）的分子克隆及序列分析

Biochim Biophys Acta. 1992 Jul 15;1131(3):333-6. doi: 10.1016/0167-4781(92)90036-y.

Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity.一种新型二肽基肽酶样2短型（DPL2-s）的分子特征，该酶在大脑中高度表达且缺乏二肽基肽酶活性。

Biochim Biophys Acta. 2006 Jan;1764(1):33-43. doi: 10.1016/j.bbapap.2005.09.013. Epub 2005 Oct 28.

Identification of the active site residues in dipeptidyl peptidase IV by affinity labeling and site-directed mutagenesis.

Biochemistry. 1992 Mar 10;31(9):2582-7. doi: 10.1021/bi00124a019.

Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.二肽基肽酶IV相关蛋白DP8和DP9在细胞黏附、迁移及凋亡中的酶外功能

FEBS J. 2006 Jun;273(11):2447-60. doi: 10.1111/j.1742-4658.2006.05253.x.

An active-site mutation (Gly633-->Arg) of dipeptidyl peptidase IV causes its retention and rapid degradation in the endoplasmic reticulum.二肽基肽酶IV的活性位点突变（甘氨酸633→精氨酸）导致其在内质网中滞留并迅速降解。

Biochemistry. 1992 Dec 1;31(47):11921-7. doi: 10.1021/bi00162a035.

An EcoRI polymorphism within the dipeptidyl peptidase IV (DPPIV) gene.

Hum Mol Genet. 1993 Sep;2(9):1507.

Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.丝氨酸蛋白酶新亚组新成员二肽基肽酶10的克隆与特性分析

Biochem J. 2003 Jul 1;373(Pt 1):179-89. doi: 10.1042/BJ20021914.

Selective cell-surface expression of dipeptidyl peptidase IV with mutations at the active site sequence.在活性位点序列存在突变的二肽基肽酶IV的选择性细胞表面表达。

Biochem Biophys Res Commun. 1992 Jun 15;185(2):776-84. doi: 10.1016/0006-291x(92)91693-k.

引用本文的文献

Complex of Proline-Specific Peptidases in the Genome and Gut Transcriptomes of Tenebrionidae Insects and Their Role in Gliadin Hydrolysis.富含脯氨酸的肽酶复合体在鞘翅目昆虫基因组和肠道转录组中的鉴定及其在麦醇溶蛋白水解中的作用。

Int J Mol Sci. 2022 Dec 29;24(1):579. doi: 10.3390/ijms24010579.

Neuronal Roles of the Multifunctional Protein Dipeptidyl Peptidase-like 6 (DPP6).多功能蛋白二肽基肽酶样 6（DPP6）的神经元作用。

Int J Mol Sci. 2022 Aug 16;23(16):9184. doi: 10.3390/ijms23169184.

The rs2619566, rs10260404, and rs79609816 Polymorphisms Are Associated With Sporadic Amyotrophic Lateral Sclerosis in Individuals of Han Ancestry From Mainland China.rs2619566、rs10260404和rs79609816基因多态性与中国大陆汉族人群散发性肌萎缩侧索硬化症相关。

Front Genet. 2021 Aug 6;12:679204. doi: 10.3389/fgene.2021.679204. eCollection 2021.

Fibroblast activation protein α in tumor microenvironment: recent progression and implications (review).肿瘤微环境中的成纤维细胞活化蛋白α：最新进展与意义（综述）

Mol Med Rep. 2015 May;11(5):3203-11. doi: 10.3892/mmr.2015.3197. Epub 2015 Jan 14.

DPP6 domains responsible for its localization and function.负责其定位和功能的二肽基肽酶6结构域。

J Biol Chem. 2014 Nov 14;289(46):32153-32165. doi: 10.1074/jbc.M114.578070. Epub 2014 Sep 4.

The transmembrane beta-subunits KCNE1, KCNE2, and DPP6 modify pharmacological effects of the antiarrhythmic agent tedisamil on the transient outward current Ito.跨膜β亚基 KCNE1、KCNE2 和 DPP6 可调节抗心律失常药替地沙米对瞬时外向电流 Ito 的药理学作用。

Naunyn Schmiedebergs Arch Pharmacol. 2009 Jun;379(6):617-26. doi: 10.1007/s00210-008-0389-1. Epub 2009 Jan 20.

Expression and function of dipeptidyl-aminopeptidase-like protein 6 as a putative beta-subunit of human cardiac transient outward current encoded by Kv4.3.二肽基氨基肽酶样蛋白6作为由Kv4.3编码的人类心脏瞬时外向电流假定β亚基的表达及功能

J Physiol. 2005 Jun 15;565(Pt 3):751-6. doi: 10.1113/jphysiol.2005.087312. Epub 2005 May 12.

Constitutive expression of CD26/dipeptidylpeptidase IV on peripheral blood B lymphocytes of patients with B chronic lymphocytic leukaemia.B 慢性淋巴细胞白血病患者外周血 B 淋巴细胞上 CD26/二肽基肽酶 IV 的组成性表达

Br J Cancer. 1999 Mar;79(7-8):1042-8. doi: 10.1038/sj.bjc.6690167.

Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression.小鼠中的臀部白色倒置破坏二肽基氨基肽酶样蛋白6并导致Kit表达失调。

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13800-5. doi: 10.1073/pnas.95.23.13800.

Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.成纤维细胞激活蛋白α的分子克隆，丝氨酸蛋白酶家族的一个成员，选择性地在上皮癌的基质成纤维细胞中表达。

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5657-61. doi: 10.1073/pnas.91.12.5657.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献