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儿童亚急性肝衰竭的临时辅助性肝移植

Temporary auxiliary liver transplantation for subacute liver failure in a child.

作者信息

Boudjema K, Jaeck D, Siméoni U, Bientz J, Chenard M P, Brunot P

机构信息

Centre de Chirurgie Viscérale et de Transplantation, Hôpital Universitaire de Hautepierre, Strasbourg, France.

出版信息

Lancet. 1993 Sep 25;342(8874):778-9. doi: 10.1016/0140-6736(93)91542-t.

Abstract

A 4-year-old boy with subacute liver failure due to hepatitis A virus underwent temporary auxiliary liver transplantation. The graft, an adult reduced liver, was implanted othotopically after a left hepatectomy had been carried out on the recipient's liver. Good liver function was immediately restored. The remaining native liver, which was 90% necrotic at the time of transplantation, regained normal histological features within 3 months. The auxiliary graft was then removed and immunosuppressive therapy stopped.

摘要

一名因甲型肝炎病毒导致亚急性肝衰竭的4岁男孩接受了临时辅助肝移植。移植物为成人缩小肝,在对受体肝脏进行左肝切除术后原位植入。肝功能立即恢复良好。移植时90%坏死的剩余自体肝脏在3个月内恢复了正常组织学特征。然后移除辅助移植物并停止免疫抑制治疗。

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