Gross E J, Hull H G, Lytton G J, Hill J A, Piersel W C
Beatrice State Developmental Center, NE 68310-3319.
Am J Ment Retard. 1993 Jul;98(1):156-64.
Neuroleptic-induced akathisia is a relatively common side effect of neuroleptic medication, characterized by a subjective sense of restlessness and the inability to sit still. It has been associated with aggression, anxiety, sleep disturbance, and suicide among patients who have mental illness. These side effects are fairly well-researched in the psychiatric literature but rarely addressed in the mental retardation literature. The prevalence, types of akathisia, differential diagnosis, and treatment were reviewed and a relevant case report presented. The importance of the diagnosis and treatment of neuroleptic-induced akathisia in individuals with mental retardation was discussed.
抗精神病药物所致静坐不能是抗精神病药物较为常见的副作用，其特征为一种主观的不安感和无法静息。在患有精神疾病的患者中，它与攻击行为、焦虑、睡眠障碍及自杀有关。这些副作用在精神科文献中已有相当充分的研究，但在智力障碍文献中很少被提及。本文回顾了静坐不能的患病率、类型、鉴别诊断及治疗，并呈现了一份相关病例报告。文中还讨论了智力障碍个体中抗精神病药物所致静坐不能的诊断和治疗的重要性。
