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[慢性β-激动剂治疗:肥厚型心肌病可能的病因学因素]

[Chronic beta-stimulant therapy: a possible etiopathogenic factor for hypertrophic cardiomyopathy].

作者信息

Speca G, Core A, Pardi L

机构信息

U.T.I.C., Ospedale Civile, Teramo.

出版信息

G Ital Cardiol. 1993 Jul;23(7):723-8.

PMID:8104836
Abstract

We herein report the case of a 37-year-old woman, referred to our Unit because of atypical chest pain, negative T waves in leads V1-6 and medio-apical hypertrophic cardiomyopathy, diagnosed by two-dimensional echocardiography. The patient suffered from status asthmaticus and consequently had been treated for a twenty year period with beta-adrenoceptor stimulating agents, corticosteroids, theophylline. No coronary stenosis was revealed by coronary angiography. The results of electrocardiographic and two-dimensional echocardiographic investigations, performed after interruption of beta-stimulations, showed a regression of hypertrophic cardiomyopathy. We suggest that hypertrophic cardiomyopathy could be induced by beta-adrenergic stimulation.

摘要

我们在此报告一名37岁女性的病例,该患者因非典型胸痛、V1 - 6导联T波倒置及经二维超声心动图诊断的中尖部肥厚型心肌病转诊至我院。患者患有哮喘持续状态,因此已接受β肾上腺素能刺激剂、皮质类固醇、茶碱治疗达20年。冠状动脉造影未显示冠状动脉狭窄。在中断β刺激后进行的心电图和二维超声心动图检查结果显示肥厚型心肌病有所缓解。我们认为肥厚型心肌病可能由β肾上腺素能刺激诱发。

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