Dedov I I, Zenkova T S, Mel'nichenko G A, Belichenko O I, Fedina I D
Probl Endokrinol (Mosk). 1993 Jul-Aug;39(4):4-7.
A total of 110 patients were examined using magnetic-resonance (MR) tomography of the brain and a special MR myelographic method. An 'empty' sella turcica was diagnosed in 29% of cases. MR tomographic criteria permitting the diagnosis of this condition were defined: a crescent-shaped hypophysis, presence of a low-intensive signal area with a glow phenomenon on MR myelogram, this area being localized intrasellarly. Different clinical variants of the empty sella turcica syndrome are demonstrated, including variants resultant from substitution therapy of thyroid hypofunction, from dopamine agonist therapy for hyperprolactinemic hypogonadism, from radiotherapy of hypophyseal adenoma. Hence, the studies have demonstrated a high efficacy of MR tomography in the diagnosis of empty sella turcica and in dynamic monitoring of patients with various hypothalamohypophyseal dysfunctions over the course of therapy.
对110名患者进行了脑部磁共振（MR）断层扫描和一种特殊的MR脊髓造影检查。29%的病例诊断为“空”蝶鞍。确定了允许诊断这种情况的MR断层扫描标准：垂体呈新月形，MR脊髓造影上存在低强度信号区且有光晕现象，该区域位于蝶鞍内。展示了空蝶鞍综合征的不同临床变体，包括甲状腺功能减退替代治疗、高催乳素血症性腺功能减退多巴胺激动剂治疗、垂体腺瘤放射治疗导致的变体。因此，这些研究表明MR断层扫描在诊断空蝶鞍以及在治疗过程中对各种下丘脑 - 垂体功能障碍患者进行动态监测方面具有很高的疗效。
