用可溶性细胞间粘附分子1检测微小核糖核酸病毒衣壳结合物的方法
Method for detection of picornavirus capsid binders with soluble intercellular adhesion molecule 1.
作者信息
Last-Barney K, Marlin S D, Pal K, Cahill-Feehan C, McNally E J, Jeanfavre D D, Merluzzi V J
机构信息
Department of Immunology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06877.
出版信息
Antimicrob Agents Chemother. 1993 Aug;37(8):1693-5. doi: 10.1128/AAC.37.8.1693.
Abstract
A method utilizing immobilized major group rhinoviruses and biotinylated soluble intercellular adhesion molecule 1 has been developed for the detection of capsid binders. Binding measurements indicate a loss in relative affinity of biotinylated soluble intercellular adhesion molecule 1 for rhinoviruses by capsid binders. This method and a new class of capsid binders are discussed.
摘要
一种利用固定化的主要群鼻病毒和生物素化可溶性细胞间黏附分子1来检测衣壳结合剂的方法已被开发出来。结合测量表明衣壳结合剂会使生物素化可溶性细胞间黏附分子1对鼻病毒的相对亲和力降低。本文讨论了该方法和一类新型的衣壳结合剂。
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本文引用的文献
1
Prevention of rhinovirus and poliovirus uncoating by WIN 51711, a new antiviral drug.新型抗病毒药物WIN 51711对鼻病毒和脊髓灰质炎病毒脱壳的预防作用
Antimicrob Agents Chemother. 1986 Jul;30(1):110-6. doi: 10.1128/AAC.30.1.110.
2
Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors.
J Virol. 1989 May;63(5):2002-7. doi: 10.1128/JVI.63.5.2002-2007.1989.
3
A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses.一种细胞黏附分子，细胞间黏附分子-1（ICAM-1），是鼻病毒的主要表面受体。
Cell. 1989 Mar 10;56(5):849-53. doi: 10.1016/0092-8674(89)90689-2.
4
The major human rhinovirus receptor is ICAM-1.主要的人鼻病毒受体是细胞间黏附分子-1（ICAM-1）。
Cell. 1989 Mar 10;56(5):839-47. doi: 10.1016/0092-8674(89)90688-0.
5
A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection.可溶性细胞间黏附分子-1抑制鼻病毒感染。
Nature. 1990 Mar 1;344(6261):70-2. doi: 10.1038/344070a0.
6
Detection of major group rhinoviruses by soluble intercellular adhesion molecule-1 (sICAM-1).通过可溶性细胞间粘附分子-1（sICAM-1）检测主要组鼻病毒
J Virol Methods. 1991 Dec;35(3):255-64. doi: 10.1016/0166-0934(91)90067-a.
7
A comparative test of fifteen compounds against all known human rhinovirus serotypes as a basis for a more rational screening program.针对所有已知人类鼻病毒血清型对15种化合物进行的比较试验，作为更合理筛选方案的基础。
Antiviral Res. 1991 Oct;16(3):213-25. doi: 10.1016/0166-3542(91)90001-8.
8
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Antimicrob Agents Chemother. 1991 Jun;35(6):1040-7. doi: 10.1128/AAC.35.6.1040.
9
Treatment of the picornavirus common cold by inhibitors of viral uncoating and attachment.
Annu Rev Microbiol. 1992;46:635-54. doi: 10.1146/annurev.mi.46.100192.003223.
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