特发性头痛的治疗可能性。1000例病例分析（作者译）

[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].

作者信息

Nattero G, Agostoni A, Brandi G, Cottino A, Gai V, Gastaldi L, Lisino F

出版信息

MMW Munch Med Wochenschr. 1975 Sep 19;117(38):1497-1500.

Abstract

According to Pearson's method (correlation coefficient) the group of improved patients is 16.88% of the expected total result (frequency of attacks regressed to 50%, 25% or 0%): for cyproheptadine, pizotifene, methysergide, methergoline, histamine, clonidine, allylpropylmalonyl urea 'p' is less than 0.001, for cinnarizine less than 0.02. For hemicrania we used cinnarizine, cyproheptadine, clonidine, histamine, pizotifene and reserpine; for cluster headache, cinnarizine, cyproheptadine, clonidine, histamine and reserpine; for tension headache, cyproheptadine; for psychogenic headache, allylpropylmalonylurea. In attacks of hemicrania or paroxysmal crises with undulant headache or persistent headache, positive statistically significant results were obtained with a combination of indomethacin, prochlorperazine and caffeine.

摘要

根据皮尔逊方法（相关系数），病情改善的患者组占预期总结果的16.88%（发作频率降至50%、25%或0%）：对于赛庚啶、苯噻啶、甲基麦角新碱、美替拉酮、组胺、可乐定、烯丙丙基丙二酰脲，“p”值小于0.001，对于桂利嗪小于0.02。对于偏头痛，我们使用了桂利嗪、赛庚啶、可乐定、组胺、苯噻啶和利血平；对于丛集性头痛，使用了桂利嗪、赛庚啶、可乐定、组胺和利血平；对于紧张性头痛，使用了赛庚啶；对于心因性头痛，使用了烯丙丙基丙二酰脲。在偏头痛发作或伴有波动性头痛或持续性头痛的阵发性危机中，吲哚美辛、丙氯拉嗪和咖啡因联合使用取得了具有统计学意义的阳性结果。