Pasechnik V I, Gianik T
Biofizika. 1978 Sep-Oct;23(5):926-7.
Young's modolus of the bilayer membrane (BLM) in the direction normal to membrane plane approximately E perpendicular changes if gramicidin A molecules are incorporated into BLM. The plot of approximately E perpendicular on membrane conductivity is a monotonic curve with saturation at BLM conductivity corresponding distances between gramicidin A dimers about 1000 angstrom. The conclusion is made that dimer formation generates drastic reorganization of BLM structure, the size of distortion zone of the membrane near the ionic channel is of the same value.
如果将短杆菌肽A分子掺入双层膜(BLM)中,那么在垂直于膜平面的方向上,双层膜的杨氏模量(Young's modulus)大约(E_{\perp})会发生变化。(E_{\perp})与膜电导率的关系曲线是一条单调曲线,在BLM电导率处达到饱和,此时短杆菌肽A二聚体之间的距离约为1000埃。得出的结论是,二聚体的形成会使BLM结构发生剧烈重组,离子通道附近膜的变形区大小相同。