Kuwabara H, Uda H, Miyaguchi M, Nagai M, Saito K, Shibanushi T
Department of Pathology, Kagawa Medical School, Japan.
Oral Surg Oral Med Oral Pathol. 1994 Jan;77(1):61-5. doi: 10.1016/s0030-4220(06)80108-8.
The clinical and morphologic features of a pigmented squamous cell carcinoma of the alveolar ridge in an 81-year-old Japanese woman are reported. The tumor was typical, well-differentiated squamous cell carcinoma but had many melanin-containing cells within it. Electron microscopy showed melanosomes in macrophages, melanocytes, and neoplastic squamous cells. Those in the neoplastic squamous cells seemed to have been excreted from the cytoplasmic processes of melanocytes.
报告了一名81岁日本女性牙槽嵴色素沉着性鳞状细胞癌的临床和形态学特征。该肿瘤为典型的高分化鳞状细胞癌,但其中含有许多含黑色素的细胞。电子显微镜检查显示巨噬细胞、黑素细胞和肿瘤性鳞状细胞内有黑素小体。肿瘤性鳞状细胞内的黑素小体似乎是从黑素细胞的细胞质突起中排出的。