Zimmermann H, Eck H
Virchows Arch A Pathol Anat Histol. 1975 Oct 7;368(1):51-9. doi: 10.1007/BF00432166.
A letal case of angiosarcoma of the liver is reported. The 38 years old chemical laboratory assistant was exposed in vinylchloride medium about 3 1/2 years. The sarcoma metastasised into many other organs. This case is the fifth one reported in the German Federal Republic, in four of the cases the patient died. VC concentration at the work place was not measured. Thrombocytopenia observed in about 80% of the VC cases was not seen. There will be possibly observed further VC-caused tumors in the population. Nevertheless there might be other even extrahepatic VC-caused tumors in man, which could be concluded by animal experimental investigations.
报告了一例致命的肝血管肉瘤病例。这位38岁的化学实验室助理在氯乙烯环境中接触约3年半。肉瘤转移至许多其他器官。该病例是德意志联邦共和国报告的第五例,其中四例患者死亡。工作场所的氯乙烯浓度未进行测量。在约80%的氯乙烯病例中观察到的血小板减少症在本病例中未出现。在人群中可能会观察到更多由氯乙烯引起的肿瘤。然而,通过动物实验研究可以推断,在人类中可能还存在其他甚至肝外的由氯乙烯引起的肿瘤。