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[氯乙烯病的病理解剖学(作者译)]

[Pathological anatomy of the vinylchloride-disease (author's transl)].

作者信息

Zimmermann H, Eck H

出版信息

Virchows Arch A Pathol Anat Histol. 1975 Oct 7;368(1):51-9. doi: 10.1007/BF00432166.

DOI:10.1007/BF00432166
PMID:810945
Abstract

A letal case of angiosarcoma of the liver is reported. The 38 years old chemical laboratory assistant was exposed in vinylchloride medium about 3 1/2 years. The sarcoma metastasised into many other organs. This case is the fifth one reported in the German Federal Republic, in four of the cases the patient died. VC concentration at the work place was not measured. Thrombocytopenia observed in about 80% of the VC cases was not seen. There will be possibly observed further VC-caused tumors in the population. Nevertheless there might be other even extrahepatic VC-caused tumors in man, which could be concluded by animal experimental investigations.

摘要

报告了一例致命的肝血管肉瘤病例。这位38岁的化学实验室助理在氯乙烯环境中接触约3年半。肉瘤转移至许多其他器官。该病例是德意志联邦共和国报告的第五例,其中四例患者死亡。工作场所的氯乙烯浓度未进行测量。在约80%的氯乙烯病例中观察到的血小板减少症在本病例中未出现。在人群中可能会观察到更多由氯乙烯引起的肿瘤。然而,通过动物实验研究可以推断,在人类中可能还存在其他甚至肝外的由氯乙烯引起的肿瘤。

相似文献

1
[Pathological anatomy of the vinylchloride-disease (author's transl)].[氯乙烯病的病理解剖学(作者译)]
Virchows Arch A Pathol Anat Histol. 1975 Oct 7;368(1):51-9. doi: 10.1007/BF00432166.
2
[A case of angiosarcoma of the liver in a worker with long exposure to vinyl chloride monomer].[一名长期接触氯乙烯单体的工人患肝血管肉瘤的病例]
Arch Belg Med Soc. 1977 Nov-Dec;35(9-10):601-22.
3
Angiosarcoma of the liver in vinyl chloride/polyvinyl chloride workers.氯乙烯/聚氯乙烯工人的肝脏血管肉瘤
J Occup Med. 1975 May;17(5):333-4.
4
Hemangiosarcoma and hepatocellular carcinoma of the liver following vinyl chloride exposure. A report of two cases.氯乙烯暴露后肝脏血管肉瘤和肝细胞癌。两例报告。
Virchows Arch A Pathol Anat Histol. 1976 Dec 27;372(3):195-203. doi: 10.1007/BF00433279.
5
Angiosarcoma of the liver in vinyl chloride/polyvinyl chloride workers. 1977 update of the NIOSH register.氯乙烯/聚氯乙烯工人的肝血管肉瘤。美国国家职业安全与健康研究所登记册1977年更新版。
J Occup Med. 1978 Jun;20(6):427-9.
6
Liver angiosarcomas occasioned by exposition to vinyl chloride.因接触氯乙烯引发的肝血管肉瘤。
Acta Pharmacol Toxicol (Copenh). 1977;41 Suppl 2:331.
7
[Hepatic angiosarcoma due to vinyl chloride. Report of 4 cases (author's transl].氯乙烯所致肝血管肉瘤。4例报告(作者译)
Gastroenterol Clin Biol. 1978 Aug-Sep;2(8-9):669-78.
8
Pathology of angiosarcoma of the liver among vinyl chloride-polyvinyl chloride workers.氯乙烯-聚氯乙烯工人中肝血管肉瘤的病理学
Ann N Y Acad Sci. 1975 Jan 31;246:268-77. doi: 10.1111/j.1749-6632.1975.tb51102.x.
9
[Vinylchloride: questionable safety].[氯乙烯:安全性存疑]
Ned Tijdschr Geneeskd. 1975 Jan 11;119(2):63-6.
10
Log normal distribution of the incubation period of liver angiosarcoma in vinyl chloride polymerization workers.氯乙烯聚合工人肝血管肉瘤潜伏期的对数正态分布。
J Occup Med. 1979 Jan;21(1):10.

引用本文的文献

1
Arsenic dose in patients with cutaneous carcinomata and hepatic hemangio-endothelioma after environmental and occupational exposure.环境和职业暴露后皮肤癌和肝血管内皮瘤患者的砷剂量。
Arch Toxicol. 1981 Apr;47(2):145-54. doi: 10.1007/BF00332356.
2
Development of hepatic angiosarcoma in man induced by vinyl chloride, thorotrast, and arsenic. Comparison with cases of unknown etiology.氯乙烯、钍造影剂和砷诱发人类肝血管肉瘤。与病因不明病例的比较。
Am J Pathol. 1978 Aug;92(2):349-76.
3
[Ultrastructure of liver damage in chronic vinyl chloride intoxication (author's transl)].

本文引用的文献

1
Circadian glucose homeostasis requires compensatory interference between brain and liver clocks.昼夜节律性葡萄糖稳态需要大脑和肝脏生物钟之间的代偿性干扰。
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14753-4. doi: 10.1073/pnas.0807861105. Epub 2008 Sep 23.
2
[CONTRIBUTION TO THE STUDY OF DISEASES CAUSED BY VINYL CHLORIDE].[氯乙烯所致疾病研究的贡献]
Med Interna (Bucur). 1963 Aug;15:967-78.
3
[Late damage from thorotrast].[钍造影剂的晚期损害]
慢性氯乙烯中毒时肝脏损害的超微结构(作者译)
Virchows Arch A Pathol Anat Histol. 1977 Apr 6;373(3):233-47. doi: 10.1007/BF00432239.
4
Hemangiosarcoma and hepatocellular carcinoma of the liver following vinyl chloride exposure. A report of two cases.氯乙烯暴露后肝脏血管肉瘤和肝细胞癌。两例报告。
Virchows Arch A Pathol Anat Histol. 1976 Dec 27;372(3):195-203. doi: 10.1007/BF00433279.
Med Welt. 1969 Jan 18;3:167-72.
4
[A study of diseases caused by vinyl chloride].[氯乙烯所致疾病的研究]
Med Lav. 1967 Apr;58(4):261-71.
5
[Liver angiosarcoma in two workers in a PVC-producing factory (author's transl)].聚氯乙烯生产工厂两名工人患肝血管肉瘤(作者译)
Dtsch Med Wochenschr. 1974 Aug 2;99(31):1598-9.
6
Angiosarcoma of liver in the manufacture of polyvinyl chloride.氯乙烯制造过程中发生的肝血管肉瘤。
J Occup Med. 1974 Mar;16(3):150-1.
7
[Chronic toxic liver lesions in the PVC (polyvinyl chloride)-producing workers].[聚氯乙烯生产工人的慢性中毒性肝损伤]
Dtsch Med Wochenschr. 1973 Nov 30;98(48):2311-4.
8
[Scleroderma like skin changes. Raynaud's syndrome and acroosteolyses in workers in the polyvinyl chloride producing industry].[硬皮病样皮肤改变。聚氯乙烯生产行业工人的雷诺综合征和肢端骨质溶解]
Dtsch Med Wochenschr. 1972 Dec 8;97(49):1922-3.
9
Hepatic disease among workers at a vinyl chloride polymerization plant.氯乙烯聚合工厂工人中的肝脏疾病。
JAMA. 1974 Oct 7;230(1):59-63.
10
Angiosarcoma of the liver in vinyl chloride/polyvinyl chloride workers.氯乙烯/聚氯乙烯工人的肝脏血管肉瘤
J Occup Med. 1974 Dec;16(12):809.