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Counts of activated blood eosinophils for monitoring asthma.

作者信息

Hed J, Halldén G

机构信息

Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden.

出版信息

Allergy. 1993;48(17 Suppl):87-93; discussion 110-1. doi: 10.1111/j.1398-9995.1993.tb04707.x.

DOI:10.1111/j.1398-9995.1993.tb04707.x
PMID:8109719
Abstract

The FOG method is a new cell membrane permeabilization technique which makes it possible to identify the eosinophils in unseparated peripheral blood and allows analyses of both surface and intracellular antigens by flow cytometry. This technique has been adapted to analyse eosinophil activity in peripheral blood from asthmatic patients by measuring the expression of the EG2-epitope on intracellular ECP.

摘要

相似文献

1
Counts of activated blood eosinophils for monitoring asthma.
Allergy. 1993;48(17 Suppl):87-93; discussion 110-1. doi: 10.1111/j.1398-9995.1993.tb04707.x.
2
Relationship of blood EG2+ eosinophils in patients with bronchial asthma.支气管哮喘患者血液中EG2+嗜酸性粒细胞的关系。
Allergol Immunopathol (Madr). 1993 May-Jun;21(3):97-9.
3
Conditions in blood sampling procedures that extend the ex vivo stability of eosinophil activity markers in peripheral blood from allergic patients and healthy controls.血液采样程序中的条件,可延长过敏患者和健康对照外周血中嗜酸性粒细胞活性标志物的体外稳定性。
Ann Allergy Asthma Immunol. 1999 Nov;83(5):413-21. doi: 10.1016/S1081-1206(10)62839-6.
4
[Eosinophil activation evaluated by using a anti-human secreted form of ECP antibody (EG2)].[采用抗人分泌型嗜酸性粒细胞阳离子蛋白抗体(EG2)评估嗜酸性粒细胞活化]
Nihon Rinsho. 1993 Mar;51(3):626-30.
5
Whole-blood flow-cytometric analysis of eosinophil EG2 expression as a marker of the pathological conditions of asthma.全血流式细胞术分析嗜酸性粒细胞EG2表达作为哮喘病理状况的标志物。
Int Arch Allergy Immunol. 1998 Sep;117 Suppl 1:77-80. doi: 10.1159/000053578.
6
A flow cytometric method for the detection of intracellular basic proteins in unseparated peripheral blood and bone marrow eosinophils.一种用于检测未分离的外周血和骨髓嗜酸性粒细胞中细胞内碱性蛋白的流式细胞术方法。
J Immunol Methods. 1996 Apr 19;190(2):245-54. doi: 10.1016/0022-1759(95)00272-3.
7
The degree of natural allergen exposure modifies eosinophil activity markers in the circulation of patients with mild asthma.自然过敏原暴露程度会改变轻度哮喘患者循环系统中的嗜酸性粒细胞活性标志物。
Allergy. 1996 Oct;51(10):697-705.
8
Eosinophil activity reflects clinical status in patients with asthma before and during a prednisolone course.嗜酸性粒细胞活性反映了哮喘患者在泼尼松龙疗程之前及期间的临床状况。
Ann Allergy Asthma Immunol. 1995 Sep;75(3):250-5.
9
Are blood eosinophil number and activity important for the development of the late asthmatic reaction after allergen challenge?
Eur Respir J Suppl. 1989 Jun;6:430s-434s.
10
Quantitative, rather than qualitative, differences in CD69 upregulation in human blood eosinophils upon activation with selected stimuli.在人血嗜酸性粒细胞经特定刺激激活后,CD69上调存在定量而非定性的差异。
Allergy. 2000 Feb;55(2):148-56. doi: 10.1034/j.1398-9995.2000.00363.x.

引用本文的文献

1
The impact of eotaxin- and IL-5-induced adhesion and transmigration on eosinophil activity markers.嗜酸性粒细胞趋化因子和白细胞介素-5诱导的黏附及迁移对嗜酸性粒细胞活性标志物的影响
Inflammation. 2000 Feb;24(1):73-87. doi: 10.1023/a:1006940109869.
2
Eotaxin increases the expression of CD11b/CD18 and adhesion properties in IL5, but not fMLP-prestimulated human peripheral blood eosinophils.嗜酸性粒细胞趋化因子增加白细胞介素5刺激而非N-甲酰甲硫氨酰-亮氨酰-苯丙氨酸预刺激的人外周血嗜酸性粒细胞中CD11b/CD18的表达及黏附特性。
Inflammation. 1998 Apr;22(2):123-35. doi: 10.1023/a:1022379821130.