Mares V
Acta Histochem. 1975;53(1):70-6.
An autoradiographic study of DNA synthesis has shown that repeated injections of 3HTdR result in marked regional differences in labelling of non-neuronal cells in the brains of young adult mice. The incidence of labelled cells was highest in the rudimentary subependymal layer. In the white matter of the corpus callosum and hippocampal commissure, the incidence of LC was several times higher than in the grey matter. Substantial difference was found in the number of labelled cells in the granular population of the olfactory bulb and the dentate gyrus of the hippocampus on the one hand, and the cerebellum on the other. Higher LI values in regions closely associated to rudimentary subependymal layer provide indirect evidence of a selective migration of dividing subependymal cells into neighbouring "target" structures.
一项关于DNA合成的放射自显影研究表明，反复注射3HTdR会导致成年幼鼠大脑中非神经元细胞标记出现显著的区域差异。标记细胞的发生率在原始室管膜下层最高。在胼胝体和海马连合的白质中，标记细胞的发生率比灰质高几倍。一方面，嗅球颗粒细胞群和海马齿状回中的标记细胞数量与另一方面小脑的标记细胞数量存在显著差异。与原始室管膜下层紧密相关区域的较高标记指数值间接证明了正在分裂的室管膜下细胞选择性迁移到相邻“靶”结构中。
