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尼日利亚卡杜纳州中度流行盘尾丝虫病社区失明和视力损害的分布及病因。卡杜纳盘尾丝虫病研究协作组

Distribution and aetiology of blindness and visual impairment in mesoendemic onchocercal communities, Kaduna State, Nigeria. Kaduna Collaboration for Research on Onchocerciasis.

作者信息

Abiose A, Murdoch I, Babalola O, Cousens S, Liman I, Onyema J, Evans J, Gregory W, Jones B

机构信息

Department of Ophthalmology, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria.

出版信息

Br J Ophthalmol. 1994 Jan;78(1):8-13. doi: 10.1136/bjo.78.1.8.

Abstract

During a field trial of ivermectin in Kaduna State, 6831 people age 5 years and above, living in 34 mesoendemic onchocercal communities in Kaduna State, northern Nigeria, were examined for ocular disease. Visual function assessments included tests of visual acuity and visual fields. A total of 185 individuals (2.7%) were bilaterally blind by acuity criteria with a further 28 blind by field constriction. The overall prevalence of blindness was 3.1%. A further 118 individuals were visually impaired by WHO criteria. Examination for the cause of blindness revealed that 43% of eyes in bilaterally blind patients were blind due to onchocerciasis. A further 11% were blind from optic atrophy much of which was probably onchocercal in origin. Glaucoma was the next most common cause of blindness in the bilaterally blind (11%). Only 6% of eyes were blind from cataract as the primary cause. In the visually impaired population cataract was the most common primary cause of impaired/blind eyes (31%), followed by onchocerciasis (19%) [corrected].

摘要

在尼日利亚北部卡杜纳州进行的伊维菌素现场试验中,对居住在卡杜纳州34个中度流行盘尾丝虫病社区的6831名5岁及以上人群进行了眼病检查。视觉功能评估包括视力和视野测试。共有185人(2.7%)按视力标准双侧失明,另有28人因视野缩窄失明。失明的总体患病率为3.1%。另有118人根据世界卫生组织标准存在视力障碍。对失明原因的检查发现,双侧失明患者中43%的眼睛因盘尾丝虫病失明。另有11%因视神经萎缩失明,其中大部分可能起源于盘尾丝虫病。青光眼是双侧失明的第二大常见原因(11%)。仅6%的眼睛因白内障作为主要原因失明。在视力障碍人群中,白内障是视力受损/失明眼睛的最常见主要原因(31%),其次是盘尾丝虫病(19%)[已校正]。

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