Yap S K, Rhodes C T, Fung H L
Am J Hosp Pharm. 1975 Oct;32(10):1039-42.
Parameters affecting the spectrophotometric kinetic assay for nitroglycerin are described. It is shown that the assay is highly specific; results are not significantly affected by many of the tablet diluents found in commercially-available nitroglycerin tablets. Further, the assay is insensitive to glycerol, nitrate, nitrite and glyceryl dinitrates. This simple, precise and specific nitroglycerin assay is well suited for routine analysis of the drug in commercial tablets and parenteral solutions in hospital pharmacies.
描述了影响硝酸甘油分光光度动力学测定的参数。结果表明该测定具有高度特异性；市售硝酸甘油片剂中发现的许多片剂稀释剂对结果没有显著影响。此外，该测定对甘油、硝酸盐、亚硝酸盐和二硝酸甘油酯不敏感。这种简单、精确且特异的硝酸甘油测定方法非常适合医院药房对市售片剂和注射剂中该药物的常规分析。
