Lafont P, Lafont J
Ann Microbiol (Paris). 1975 Jan;126(1):97-106.
After culture of Aspergillus flavus in synthetic medium supplemented with aflatoxin B1, the level of mycotoxin decreases rapidly during the course of two or three days. Later, in the case of highly toxinogenic strains, a reduction in the production of aflatoxins is observed; whereas, conversely, in the case of low toxinogenesis are obtained in the presence of high levels of the mycotoxin. With all strains of A. flavus, the presence of aflatoxin B1 in the medium at the time of inoculation, moderately limits the growth of mycelium but it has a little effect on the conidial sporulation.
在添加黄曲霉毒素B1的合成培养基中培养黄曲霉后,霉菌毒素水平在两到三天内迅速下降。之后,对于高毒素产生菌株,观察到黄曲霉毒素产量降低;相反,对于低毒素产生菌株,在高浓度霉菌毒素存在的情况下仍能产生毒素。对于所有黄曲霉菌株,接种时培养基中黄曲霉毒素B1的存在适度限制了菌丝体的生长,但对分生孢子形成影响较小。