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短期锂治疗对豚鼠白细胞、肝脏和肌肉碳水化合物代谢的影响。

The effect of short term lithium treatment on the leukocyte, liver and muscle carbohydrate metabolism of guinea-pigs.

作者信息

Altan N, Engin A, Hizel N, Ongun O, Cevik C

机构信息

Department of Biochemistry, Faculty of Medicine, University of Gazi, Ankara, Turkey.

出版信息

Gen Pharmacol. 1993 Nov;24(6):1491-3. doi: 10.1016/0306-3623(93)90441-y.

Abstract
  1. The effect of lithium treatment on the leukocyte, liver and muscle glycogen levels of guinea-pigs has been studied. 2. A 4-week treatment with lithium chloride (5 mmol/l i.p. in saline) increased leukocyte, liver and muscle glycogen and decreased blood glucose levels. 3. These results strongly suggest that a lithium-induced insulin-like effect may be related to the long term effect.
摘要
  1. 研究了锂治疗对豚鼠白细胞、肝脏和肌肉糖原水平的影响。2. 用氯化锂(5毫摩尔/升,腹腔注射于生理盐水中)进行4周治疗,可增加白细胞、肝脏和肌肉糖原含量,并降低血糖水平。3. 这些结果有力地表明,锂诱导的胰岛素样效应可能与长期效应有关。

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