Fréminet A, Leclerc L
J Physiol (Paris). 1980;76(8):877-80.
The effect of a 48 hr fasting period on liver and muscle glycogen was studied in rats and guinea pigs. Total content of glycogen in the liver was similar in both species of fed animals and was totally exhausted after the fasting period. Muscle glycogen was twice as high in fed guinea pigs as in fed rats. The loss during fasting in guinea pigs was also twice that in rats. The differences in glycogen stores may explain the different metabolic response to fasting previously observed in the two species : hypoglycemia and decreased glucose production in fasted rats and constancy of these parameters in fasted guinea pigs.
研究了48小时禁食期对大鼠和豚鼠肝脏及肌肉糖原的影响。在两种喂食动物中，肝脏糖原的总含量相似，禁食期后完全耗尽。喂食的豚鼠肌肉糖原含量是喂食大鼠的两倍。豚鼠禁食期间的糖原损失也是大鼠的两倍。糖原储备的差异可能解释了先前在这两个物种中观察到的对禁食的不同代谢反应：禁食大鼠出现低血糖和葡萄糖生成减少，而禁食豚鼠这些参数保持恒定。
