Garg H K, Singal K C, Arshad Z
Department of Pharmacology, J. N. Medical College, A.M.U., Aligarh.
Indian J Physiol Pharmacol. 1993 Oct;37(4):318-22.
Pregnant women in different trimesters of pregnancy were divided into control (n = 58) and study (n = 104) groups. Study group subjects were given 45 mg zinc/p.o./day as 200 mg 'zinc sulphate tablets from the day of reporting till term. Body zinc status was clinically assessed by 'zinc taste test'. Blood samples were drawn at the same time and serum zinc levels measured. Zinc taste test scores decreased with advancement of pregnancy (P < 0.05) and increased significantly following zinc administration (P < 0.05). Serum zinc level declined significantly with advancement of pregnancy (P < 0.001). Following zinc administration, serum zinc level increased significantly (P < 0.001). Accuracy of zinc taste test in individual cases ranged between 70 and 100 percent. On the whole, zinc taste test was well correlated with serum zinc level, and provides a fair idea of zinc deficiency.
处于不同孕期的孕妇被分为对照组(n = 58)和研究组(n = 104)。研究组受试者从报到之日起至足月,每天口服45毫克锌,以200毫克硫酸锌片的形式服用。通过“锌味觉试验”对身体锌状态进行临床评估。同时采集血样并测量血清锌水平。锌味觉试验评分随孕期进展而降低(P < 0.05),补锌后显著升高(P < 0.05)。血清锌水平随孕期进展而显著下降(P < 0.001)。补锌后,血清锌水平显著升高(P < 0.001)。个体病例中锌味觉试验的准确率在70%至100%之间。总体而言,锌味觉试验与血清锌水平密切相关,能大致反映锌缺乏情况。