Ogden J A, Ganey T M, Light T R, Greene T L, Belsole R J
Shriners Hospitals for Crippled Children, Tampa.
J Pediatr Orthop. 1994 Jan-Feb;14(1):78-82. doi: 10.1097/01241398-199401000-00016.
Direct ossification extending from the metaphysis into the epiphysis preceded and continued to be more mature than formation and expansion of the typical epiphyseal ossification center at the opposite end of each longitudinal bone of the hand and foot. Direct metaphyseal to epiphyseal ossification usually started centrally and expanded hemispherically, replacing both physeal and epiphyseal cartilage simultaneously. When remnants of the "physis" were retained, however, while juxtaposed epiphyseal cartilage was replaced, a pseudoepiphysis formed. Three basic patterns of pseudoepiphysis formation were evident: (a) a central osseous bridge, (b) a peripheral osseous bridge, and (c) multiple bridging. In each condition, the remnant of the "physis" lacked typical cell columns capable of contributing to the postnatal longitudinal growth of the involved bone. Pseudoepiphyses were well formed by 4-5 years and coalesced with the rest of the bone months to years before skeletal maturation was attained at the opposite epiphyseal end.
从干骺端延伸至骨骺的直接骨化先于手足各长骨另一端典型骨骺骨化中心的形成并持续更为成熟，且向该中心扩展。干骺端至骨骺的直接骨化通常始于中央并呈半球形扩展，同时替代骺板和骨骺软骨。然而，当“骺板”残余部分保留时，相邻的骨骺软骨被替代，形成一个假骨骺。假骨骺形成有三种基本模式：(a)中央骨桥，(b)周边骨桥，(c)多个骨桥。在每种情况下，“骺板”残余部分缺乏能够促进受累骨骼出生后纵向生长的典型细胞柱。假骨骺在4 - 5岁时形成良好，并在对侧骨骺端达到骨骼成熟前数月至数年与其余骨骼融合。
