三匹马继发于淋巴细胞白血病的全血细胞减少症。

Pancytopenia secondary to lymphoid leukemia in three horses.

作者信息

Lester G D, Alleman A R, Raskin R E, Meyer J C

机构信息

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136.

出版信息

J Vet Intern Med. 1993 Nov-Dec;7(6):360-3. doi: 10.1111/j.1939-1676.1993.tb01031.x.

DOI:10.1111/j.1939-1676.1993.tb01031.x

PMID:8114032

Abstract

Pancytopenia was observed in two 3-year-old geldings and one 11-year-old mare. All horses had a brief history (2 days to 4 weeks) of fever, anorexia, and depression. One of the three horses had blast cells present on a peripheral blood smear. Examination of the bone marrow showed substantial infiltration with neoplastic lymphoid cells. At necropsy, neoplastic cells were restricted to the bone marrow in one horse, present in bone marrow, liver, and spleen in the second horse, and reported in multiple tissues in the third horse, including bone marrow, kidneys, lung, myocardium and lymph nodes. The value of a bone marrow aspirate and core biopsy in the investigation of pancytopenia is highlighted.

摘要

在两匹3岁的 geldings（可能是特定品种的马，未找到准确释义）和一匹11岁的母马中观察到全血细胞减少。所有马匹都有短暂的病史（2天至4周），表现为发热、厌食和精神沉郁。三匹马中的一匹外周血涂片上有原始细胞。骨髓检查显示有大量肿瘤性淋巴细胞浸润。尸检时，一匹马的肿瘤细胞局限于骨髓，第二匹马的肿瘤细胞存在于骨髓、肝脏和脾脏，第三匹马的肿瘤细胞见于多个组织，包括骨髓、肾脏、肺、心肌和淋巴结。强调了骨髓穿刺和活检在全血细胞减少症调查中的价值。